Biological Resources Unit

The Biological Resources Unit provides support to all scientists who conduct laboratory animal work as part of their research at CRUK Manchester Institute. We breed and use mice only.  

The BRU is divided into two teams: the Transgenic Breeding Team and the Experimental Team.  

BRU Transgenic Breeding Team

The BRU Transgenic Breeding Team provides expertise on the breeding, maintenance and tissue archival of genetically altered mice and expert advice.  The unit maintains around 140 breeding lines of transgenic mice and is staffed by a team of professional animal technologists. Services include genotyping (through an external provider), the import and export of transgenic mice, and maintenance of transgenic colonies.

Experimental Team

The BRU Experimental Team provides a comprehensive support service to the research groups. The team of 11 technicians keep the research unit running smoothly, provide high quality day to day animal care and between them have a wide range of expertise in different experimental procedures. Over the last couple of years the breadth of in vivo research at the institute has expanded dramatically and the team have worked closely with the researchers to develop new surgical and imaging models, providing animal welfare advice and practical input. Other key roles include the provision of quality, well-structured training for new licensee’s joining the institute, promotion and implementation of the 3Rs and involvement in public engagement events.