Selected Publications
Fadlullah MZ, Neo WH, Lie-A-Ling M, Thambyrajah R, Patel R, Mevel R, Aksoy I, Do Khoa N, Savatier P, Fontenille L, Baker SM, Rattray M, Kouskoff V, Lacaud G. (2022)
Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE.
Blood 139(3):343-356. PubMed abstract (PMID: 34517413)
Neo WH, Meng Y, Rodriguez-Meira A, Fadlullah MZH, Booth CAG, Azzoni E, Thongjuea S, de Bruijn MFTR, Jacobsen SEW, Mead AJ, Lacaud G. (2021)
Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors.
Nature Communications 12(1):7019. PubMed abstract (PMID: 34857757)
Mevel R, Steiner I, Mason S, Galbraith LC, Patel R, Fadlullah MZ, Ahmad I, Leung HY, Oliveira P, Blyth K, Baena E, Lacaud G. (2020)
RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development.
Elife 9:e60225. PubMed abstract
Lie-A-Ling M, Marinopoulou E, Lilly AJ, Challinor M, Patel R, Lancrin C, Kouskoff V, Lacaud G. (2018)
Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium.
Development 145(5). PubMed abstract
Draper JE, Sroczynska P, Fadlullah MZH, Patel R, Newton G, Breitwieser W, Kouskoff V, Lacaud G. (2018)
A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects.
PLoS Genetics 14(1):e1007127. PubMed abstract
Stefanska M, Batta K, Patel R, Florkowska M, Kouskoff V, Lacaud G. (2017)
Primitive erythrocytes are generated from hemogenic endothelial cells.
Scientific Reports 7(1):6401. PubMed abstract
Draper JE, Sroczynska P, Leong HS, Fadlullah MZH, Miller C, Kouskoff V, Lacaud G. (2017)
Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors.
Blood 130(3):271-284. PubMed abstract
Thambyrajah R, Mazan M, Patel R, Moignard V, Stefanska M., Marinopoulou E, Li Y, Lancrin C, Clapes T, Möröy T, Robin C, Miller C, Cowley S, Göttgens B, Kouskoff V, Lacaud G. (2016)
GFI1 proteins orchestrate the emergence of Haematopoietic Stem Cells in the AGM through recruitment of LSD1.
Nature Cell Biology 18(1):21-32. PubMed abstract
Lie-A-Ling M, Marinopoulou E, Li Y, Patel R, Stefanska M, Bonifer C, Miller C, Kouskoff V, Lacaud G. (2014)
RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.
Blood 124(11):e11-20. PubMed abstract
Lancrin C, Sroczynska P, Stephenson C, Allen T, Kouskoff V, Lacaud G. (2009)
The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage.
Nature 457(7231):892-5. PubMed abstract