Selected Publications
Matthew Roberts, Julia Ogden, A S Md Mukarram Hossain, Alastair Kerr, Caroline Dive, Jennifer E Beane, Carlos Lopez-Garcia.
Interrogating the Precancerous Evolution of Pathway Dysfunction in Lung Squamous Cell Carcinoma Using XTABLE.
bioRxiv 2022.05.06.490640; doi: https://doi.org/10.1101/2022.05.06.490640
Wilson SJ, Howarth PJ, Thomas MJ, Adcock IM, López-García C.
CEACAM5 is an IL-13-regulated epithelial gene that mediates transcription in type-2 (T2) high severe asthma.
Allergy [Epub 2 Aug 2022] Article (PMID: 35916059).
Gronroos E, López-García C. (2018)
Tolerance of Chromosomal Instability in Cancer: Mechanisms and Therapeutic Opportunities.
Cancer Research 78(23):6529-6535. PubMed abstract (PMID: 30420473)
López-García C, Sansregret L, Domingo E, McGranahan N, Hobor S, Birkbak NJ, Horswell S, Grönroos E, Favero F, Rowan AJ, Matthews N, Begum S, Phillimore B, Burrell R, Oukrif D, Spencer-Dene B, Kovac M, Stamp G, Stewart A, Danielsen H, Novelli M, Tomlinson I, Swanton C. (2017)
BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
Cancer Cell 31(1):79-93. PubMed abstract (PMID: 28073006)
Sansregret L, Patterson JO, Dewhurst S, López-García C, Koch A, McGranahan N, Chao WCH, Barry DJ, Rowan A, Instrell R, Horswell S, Way M, Howell M, Singleton MR, Medema RH, Nurse P, Petronczki M, Swanton C. (2017)
APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.
Cancer Discovery 7(2):218-233. PubMed abstract (PMID: 28069571)
Cremades A, Del Rio-Garcia J, Lambertos A, López-Garcia C, Peñafiel R. (2016)
Tissue-specific regulation of potassium homeostasis by high doses of cationic amino acids.
Springerplus 5:616. PubMed abstract (PMID: 27330882)
López-Garcia C, Ramos-Molina B, Lambertos A, López-Contreras AJ, Cremades A, Peñafiel R. (2013)
Antizyme inhibitor 2 hypomorphic mice. New patterns of expression in pancreas and adrenal glands suggest a role in secretory processes.
PLoS One 8(7):e69188. PubMed abstract (PMID: 23874910)
Lopez-Garcia C, Klein AM, Simons BD, Winton DJ. (2010)
Intestinal stem cell replacement follows a pattern of neutral drift.
Science 330(6005):822-5. PubMed abstract (PMID: 20929733)