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CRUK National Biomarker Centre part of newly launched multi-million-pound UK-wide team to study immunotherapy response
06 Oct 2024
NBC and MI are contributing to a nationwide team of universities, hospitals and industry that have launched a new platform to understand immunotherapy response and side effects in cancer.
Biological Resources Unit win first prize for poster
01 Oct 2024
Members of the BRU win first prize for refinement project at Institute of Animal Technology poster event.
Institute Group Leader awarded European Research Council Starting Grant
05 Sep 2024
Evangelos Giampazolias received £1.8m in EU funding to pursue cutting-edge research in cancer immunity in Manchester.
The Paterson Building officially opens
17 Jul 2024
Staff, funders, donors and special guests attended the official opening of the Paterson Building.
Institute student wins best presentation prize
28 Jun 2024
PhD student Charlotte Russell awarded best presentation prize at the UK Cancer Metabolism Network Meeting 2024.
The launch of the Cancer Research UK National Biomarker Centre
14 Jun 2024
The CRUK National Biomarker Centre officially opened during a spectacular launch event.
Institute student wins best poster prize at meeting
31 May 2024
Maria Koufaki wins best poster prize at the Cancer and the Host: Tumour Immunology meeting.
British Science Week 2024
14 Mar 2024
This week we've been visiting Manchester Museum as part of British Science Week 2024, showing how DNA sequencing support cancer research.
Institute animal technician wins Andrew Blake Tribute Award
13 Mar 2024
BRU Scientific Officer Tom Bosley wins the Andrew Blake Tribute Award
Paterson Cancer Research Building Wins Greater Manchester Chamber of Commerce Building of the Year Award 2023
01 Mar 2024
A triumphant milestone in the Paterson Building’s journey from ashes to excellence.
Raymond Schofield Awarded 2024 Wiley Prize in Biomedical Sciences age 98
26 Feb 2024
Former Paterson Laboratories scientist Ray Schofield receives Wiley Prize 45 years after discovery.
Manchester cancer expert backs call for urgent investment in research
22 Feb 2024
Caroline Dive is one of the world’s top scientists to sign a letter asking for philanthropic support to transform cancer research.
Institute 3Rs poster event relaunched
25 Jan 2024
Manchester Institute relaunches 3Rs poster event at the Paterson Building.
The Edith Paterson Prize 2023
08 Jan 2024
The Edith Paterson Prize for Best Young Scientist of 2023 goes to Luciano Nicosia from Leukaemia Biology.
Fundraising for Movember
04 Dec 2023
Purchase Officer David Jenkins raises record funds for Movember this year.
Fellowship funding success
04 Sep 2023
Amaya Virós wins prestigious CRUK Advanced Clinician Scientist Fellowship.
Success for Systems Oncology
03 Jul 2023
Congratulations to Claus Jorgensen and his group for an outstanding QQR result.
Success at the Division of Cancer Sciences Postgraduate Research Showcase
29 Jun 2023
PhD students Maria Koufaki and Charles Earnshaw win prizes at DCS Postgraduate Research Showcase.
International PhD Student Cancer Conference 2023
26 Jun 2023
Success for our students at this years’ International PhD Student Cancer Conference
Relocation of the CRUK Manchester Institute is underway
19 Jun 2023
We are excited to announce that our relocation plans are now well underway as we make our move to the new research centre in Withington, Manchester
New technology explains how cancer cells evolve and become resistant to drugs
08 May 2023
Researchers explore cell plasticity to explain how cancer evades treatment
Researchers discover novel drug target to help treat prostate cancer
17 Apr 2023
Collaboration reveals new group of proteins that could be used to improve cancer patient survival.
XTABLE: a new tool to unravel the mechanisms of pre-cancerous lesions
13 Mar 2023
Institute scientists develop open-source platform that could be a game-changer in the early detection of lung cancer.
The secret to treating leukaemia?
27 Feb 2023
Institute scientists target the ‘quiet’ regions of the genome to treat blood cancer.
Manchester ECMC receives major funding to help find new cancer treatments
24 Jan 2023
Manchester Experimental Cancer Medicine Centre success in renewal bid.
CRUK Manchester Institute 2022 Edith Paterson Prize winner
19 Jan 2023
Keren Dawson wins 2022 Edith Paterson Prize
New Cancer Biomarker Centre Deputy Director appointed
03 Jan 2023
Dominic Rothwell is our new Deputy Director of the CRUK Manchester Institute Cancer Biomarker Centre.
Institute scientists and biotech company present early clinical data
12 Dec 2022
Tim Somervaille and Luciano Nicosia present new data in collaboration with CellCentric.
Scientists reveal new protein-chromatin interactions behind leukaemia cell differentiation block
28 Oct 2022
The Somervaille lab provides insight into protein interactions on chromatin and the cell differentiation block in Acute Myeloid Leukaemia.
Institute Director receives Lifetime Achievement Award
24 Oct 2022
Caroline Dive receives International Society of Liquid Biopsy Lifetime Achievement Award.
Encouraging Inclusivity in Technology Clinical Trials Project wins award
19 Oct 2022
digital ECMT win a Greater Manchester Cancer Award for inclusivity in trials project.
Adding a piece to the puzzle: improving the prediction of patient response to cancer immunotherapy
05 Oct 2022
Institute scientists discover the immune system can predict patient response to cancer treatment.
Blood test paves way for early detection and personalised treatment options for patients with lung cancer
08 Aug 2022
Institute scientists reveal non-invasive method for early detection and monitoring of lung cancer patients.
Uncovering and targeting KRAS’s partners in crime in pancreatic cancer
25 Jul 2022
Postdoc Nasir Haider is awarded a Pancreatic Cancer UK Career Foundation Fellowship.
Institute postdoc wins 2022 BACR Chris Marshall Prize
04 Jul 2022
Postdoc Tim Budden wins BACR Chris Marshall Prize for Cell Signalling.
The case for banning sunbeds
25 May 2022
Researchers from Manchester and Australia outline the health and economic benefits of banning indoor tanning beds.
Researchers find blood test to guide therapy and improve survival in cancer patients
10 Mar 2022
Institute scientists among first to discover predictive biomarker that improves patient survival.
Blood test to detect cancer returning reaches final trial stage
24 Jan 2022
Blood test brought to the clinic for the first time to help patients with early-stage melanoma.
Encouraging inclusivity in technology clinical trials
10 Jan 2022
Our digitalECMT address the challenges of using technology in healthcare.
November is Lung Cancer Awareness Month
30 Nov 2021
Find out how our scientists are overcoming the challenges of lung cancer
Institute Fellow receives Melanoma Research Alliance and Rosetrees Trust Young Investigator Award
26 Jul 2021
Amaya Viros wins prestigious Melanoma Research Alliance and Rosetrees Trust Young Investigator Award.
Institute Weiss Medal Winner
14 Jul 2021
Rob Bristow awarded Association for Radiation Research 2021 Weiss Medal.
Women’s stronger immune response could protect from some skin cancers
03 Jun 2021
Amaya Viros and colleagues show how the female immune system may protect women from developing aggressive skin cancer.
Institute scientists reveal how common anti-inflammatory drugs boost immunotherapy cancer treatments
26 May 2021
Santiago Zelenay and team show immunotherapy works better in combination with anti-inflammatory drugs that target COX-2.
Institute success on national Oncology Development Programme
17 May 2021
Caroline Springer and Richard Marais successfully reached the development phase of the Alderley Park Oncology Development Programme.
Ultraviolet light-induced collagen degradation inhibits melanoma invasion
12 May 2021
Amaya Viros and Skin Cancer and Ageing team show how sun exposure degrades collagen in the skin that reduces skin cancer invasion.
Caroline Dive receives Distinguished Service Award
01 Feb 2021
Caroline Dive honoured with IASLC Distinguished Service Awards for her contribution to the field of thoracic cancers.
A new recruit to The Brilliant Club
12 Jan 2021
PhD Student Millie Jones set to tutor pupils from underrepresented backgrounds
Ultraviolet radiation causes rare type of eye cancer
11 Jan 2021
New research identifies mutations in a rare eye cancer that could be targeted by drugs used to treat skin cancer.
Dexter Award 2020
04 Jan 2021
Dexter Award for the Best Young Scientist of 2020 awarded to Wendy Trotter.
Professor Caroline Dive named Interim Director of the Cancer Research UK Manchester Institute
01 Jan 2021
At the start of 2021, we welcome Caroline Dive as Interim Director.
Bruntwood SciTech at Alderley Park launches breakthrough Oncology Development Programme
09 Nov 2020
This national programme, supported by CRUK and Innovate UK, aims to find and develop innovations to improve cancer diagnosis and treatment.
A new way of taming the cell cycle with cancer drugs
14 Oct 2020
Iain Hagan and Wendy Trotter develop a new approach to synchronise the cell division cycle of an entire population of human cells in culture.
AML: Understanding gene activation to find novel therapeutic targets
05 Aug 2020
Bettina Wingelhofer secures John Goldman Fellowship from Leukaemia UK.
Science Writing Competition Winner
07 Jul 2020
PhD student Alex du Feu wins first place in 2020 Bio-Rad Science Writing Competition
CRUK MI scientist on the frontline at coronavirus mega-lab
19 May 2020
Isabelle Thompson is among many volunteers who are testing patient samples for coronavirus at the Lighthouse Lab at AP.
CRUK MI scientist on the frontline at coronavirus mega-lab
18 May 2020
Sophie Richardson is among many volunteers who are testing patient samples for coronavirus at the Lighthouse Lab at AP.
CRUK MI scientist on the frontline at coronavirus mega-lab
15 May 2020
Dominic Rothwell leads volunteers testing patient samples for coronavirus at the Lighthouse Lab at AP
CRUK MI PhD student shares experience of COVID-19 lockdown
12 May 2020
PhD student Zoe Lee talks to Royal Society about the impact of the lockdown on her research.
How the CRUK Manchester Institute are supporting the national effort in SARS-CoV-2 testing
07 May 2020
CRUK MI staff work with AP Lighthouse Laboratory to support SARS-CoV-2 testing.
COVID-19: CRUK MI scientist manufacturing PPE
05 May 2020
Our Steve Bagley has produced over 200 head straps to support NHS workers on the frontline.
COVID-19 Response – our measures to help prevent the spread of the virus
24 Mar 2020
CRUK Manchester Institute has suspended all non-essential access across our site until further notice.
New CRUK Accelerator Award for Digital Clinical Trials to UpSMART Experimental Cancer Medicine Centres
02 Mar 2020
New Accelerator awarded to the CRUK MI Cancer Biomarker Centre and partners to ‘digitalise’ experimental cancer medicine centres across the UK, Italy and Spain.
Dexter Award 2019
24 Jan 2020
The Institute’s Dexter Award 2019 is jointly awarded to Alice Lallo and Mark Williams.
digital Experimental Cancer Medicine Team win Patient Engagement award
10 Dec 2018
digitalECMT receives the Patient Engagement award at the Microsoft Health & Artificial Intelligence Summit.
Exploring cells within cells
13 Sep 2018
Patricia Muller and colleagues show that a mutant gene is linked to the formation of cell-in-cell structures.
Institute Clinical Fellow wins McElwain Prize
07 Sep 2018
Rebecca Lee has won the Association of Cancer Physicians McElwain translational research prize for “Circulating tumour DNA as a tool to guide clinical decision making in melanoma”.
Spatio-temporal regulation of key Rho-family protein is linked to perinuclear actin cap function
08 Aug 2018
Nature Communications study provides new insights into the perinuclear actin cap and nuclear morphology
Honorary appointment for outgoing CEO of CRUK
16 Jul 2018
Sir Harpal Kumar, the eminent and influential Chief Executive of Cancer Research UK, has been appointed an honorary Chair in Cancer Sciences in the Faculty of Biology, Medicine and Health at The University of Manchester.
Distinguished Achievement Award Winners
02 Jul 2018
Stuart Pepper, Caroline Wilkinson and Kenny Nolan win Team Distinguished Achievement Award
Acteria Prize winner
01 Jul 2018
Eduardo Bonavita wins Acteria Prize for the best PhD thesis in Immunology in Europe
Winner of the 2018 BACR Chris Marshall Prize for Cell Signalling
11 Jun 2018
Zoi Diamantopoulou receives prestigious BACR Chris Marshall Prize for Cell Signalling.
CRUK Manchester Institute researcher receives Fulbright Award to the US
16 May 2018
Postdoctoral researcher, Dr Stuart Williamson, receives Fulbright Award to the US
Institute Director elected Fellow of the Royal Society
10 May 2018
The Royal Society has granted its prestigious fellowship to Institute Director Professor Richard Marais FRS.
Truncation- and motif-based pan-cancer analysis reveals tumour-suppressing kinases
17 Apr 2018
A kinase domain–focused functional genomic screen reveals loss-of-function mutations in a JNK pathway kinase in gastric cancer.
New world-class cancer centre to open in Manchester
11 Apr 2018
Ambitious, world-class cancer research facility to be built on the site of the Paterson Building.
IDEAYA Biosciences and Cancer Research UK Announce Partnership Agreement to Develop Small Molecule Inhibitors of PARG
13 Mar 2018
IDEAYA Biosciences enters into partnership agreement with CRUK’s Commercial Partnerships Team and the Drug Discovery Unit to develop small molecule inhibitors of PARG.
Institute postdoc awarded Kay Kendall Leukaemia Fund Junior Research Fellowship
12 Feb 2018
Dr Isabel Romero-Camarero has been awarded a prestigious Kay Kendall Leukaemia Fund Junior Research Fellowship, which supports outstanding individuals wishing to pursue research into haematological malignancies.
Institute researcher invited to give prestigious conference lecture
30 Jan 2018
Dr Amaya Virós to deliver the Rising Star Lecture at the 2018 International Investigative Dermatology Meeting.
Prof Caroline Dive awarded CBE in the New Year's Honours list
30 Dec 2017
Our Deputy Director Professor Caroline Dive has been awarded a CBE in the New Year's Honours list for services to Cancer Research.
Society for Melanoma Research chooses Manchester for 2018 Congress
17 Dec 2017
SMR announces that their 15th International Congress will be held in Manchester in October 2018
3Rs star wins the 2018 Andrew Blake Tribute Award
11 Dec 2017
Melanie Galvin is to receive the Andrew Blake Tribute Award for 2018.
Institute Group Leader to receive €2million ERC funding
28 Nov 2017
Institute Group Leader Claus Jørgensen is one of 329 top researchers to be awarded an ERC Consolidator Grant.
University Medal of Honour for Professor Nic Jones
28 Nov 2017
World-leading cancer researcher Nic Jones has been awarded the Medal of Honour.
CRUK Manchester Institute to set up major base at Alderley Park
24 Nov 2017
Alderley Park, the largest bioscience campus in the UK, is to be CRUK Manchester Institute's interim home.
Institute scientist named as ‘Future Leader’ by Cancer Research UK
06 Nov 2017
Dr Santiago Zelenay receives Cancer Research UK’s Future Leader Prize at the NCRI Cancer Conference in Liverpool this week.
Expert in cancer therapeutics to lead Drug Discovery Unit
22 Jun 2017
Professor Caroline Springer, an expert in cancer therapeutics, will join the Institute to lead our Drug Discovery Unit.
New insight into reining in bowel cancer spread
20 Jun 2017
Our researchers discover a two-pronged defence against aggressive bowel cancer.
3Rs award for BRU
06 Apr 2017
BRU wins Janet Wood Innovation Award for introducing cable tie “swings” to improve welfare.
Manchester scientists are to receive £1.2million to help transform pancreatic cancer treatment
24 Mar 2017
Scientists from the Institute will receive funding from Cancer Research UK to develop new treatments for pancreatic cancer using a network of clinical trials.
Institute Director to receive prestigious Léopold Griffuel Award
20 Mar 2017
Professor Richard Marais will receive one of the most prestigious European awards for cancer research: the Léopold Griffuel Award in Translational and Clinical Research.
The CRT Pioneer Fund and Cancer Research UK Manchester Institute nominate cancer drug candidate
20 Jan 2017
CRT Pioneer Fund will further develop RET inhibitors through a collaboration with our Drug Discovery Unit.
Pseudo-blood vessels linked to poor survival in lung cancer
21 Dec 2016
Researchers discover a subset of CTCs express a vascular endothelial cadherin associated with vasculogenic mimicry.
Cancer Research UK Manchester Institute wins an Understanding Animal Research Openness Award
06 Dec 2016
CRUK Manchester Institute has been recognised for helping to further the communication of animal research in the UK.
Blood test could predict best treatment for lung cancer
21 Nov 2016
A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment.
Liquid biopsy reveals ‘Jekyll and Hyde’ nature of rare melanoma
09 Nov 2016
Using blood the study shows how in future tumour evolution could be monitored without invasive biopsies.
Christie consultant made professor
03 Oct 2016
Tim Somervaille, researcher and honorary consultant, has been honoured with a professorship from The University of Manchester
Scientist’s dedication to charity earns national praise
13 Sep 2016
Allan Jordan has received a national award from Cancer Research UK in recognition of his outstanding contribution to the cause.
Exploring how a lack of oxygen gives cancer the evolutionary advantage
02 Sep 2016
Researchers show how hypoxia in cancer cells can shift protein-coding genes into becoming non-coding ‘dark matter’.
Cellular signalling 'tug-of-war' proteins identified
16 Aug 2016
Our scientists explain some of the contradictory behaviour of Rac1.
Gold LEO Pharma Research Foundation Award
12 Aug 2016
Dr Amaya Virós wins the Gold Award from LEO Pharma Research Foundation for exceptional contributions to dermatology research.
Twin blood cell growth proteins are not identical
01 Aug 2016
Our scientists have shown that a pair of proteins involved in the development of blood cells may have different roles to play, with one apparently much more implicated in certain types of leukaemia.
Wilsede Best Poster Award
18 Jul 2016
Anne Largeot wins Best Poster Award at the XXI Wilsede “Modern Trends in Human Leukemia and Cancer” meeting.
New European Consortium launched to fight eye cancer
13 Jul 2016
The Cancer Research UK Manchester Institute will be a partner in a new European Consortium to foster research on metastatic uveal melanoma and identify new treatments for this serious disease.
European cancer scientists converge on Manchester to share latest research
09 Jul 2016
Cancer experts from around Europe converge on Manchester to share expertise with our world-leading scientists at a special Congress.
IPSCC Prize winner
04 Jul 2016
Emma Williams was awarded Best Talk Prize at the 10th International PhD Student Cancer Conference.
Cancer Research UK Manchester Institute joins forces with U.S. ‘Cancer Moonshot’ to develop advanced cancer cell detection technology
29 Jun 2016
Professor Caroline Dive will work with a team from the US to radically accelerate progress against cancer, in one of the first international collaborations inspired by US Vice President Joe Biden’s Cancer Moonshot.
Caroline Dive wins AstraZeneca Prize for Women in Pharmacology
27 Jun 2016
Professor Caroline Dive has recently been awarded a prestigious British Pharmaceutical Society prize.
Our researchers lead the way in cutting-edge research
22 May 2016
Our scientists will play a key role in ground-breaking research into the final stages of cancer.
Cancer cells turn healthy cells to the ‘dark side’
13 May 2016
A breakthrough study sheds light on how cancer cells and normal cells communicate with each other and could open up new approaches to cancer treatment.
CRUK Grand Challenge five: build a ‘Google Street View’ for cancer shortlisted
02 May 2016
Caroline Dive is a team member shortlisted to develop a method for generating personalised 4D atlases of cancers.
Institute postdoctoral scientist honoured in prestigious Biochemical Society Awards
08 Apr 2016
Dr Maria Romina Girotti is one of four exceptional early career researchers honoured in the 2017 Awards.
Scientists identify possible double whammy to attack leukaemia
07 Apr 2016
Our scientists have identified a potential double drug combination against B-cell acute lymphoblastic leukaemia.
Researchers find a genetic new target for most common lung cancer
22 Mar 2016
Our researchers have identified mutations in lung cancer that are key to tumour growth, offering a new way to differentiate and treat some patients with the disease.
Blood test may give early warning of skin cancer relapse
07 Mar 2016
A blood test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing.
Illuminating one dark spot in the genetics of bowel cancer
10 Feb 2016
Our scientists have explored the role of one particular cell signalling protein in bowel cancer, and found that its mutation promotes tumour growth.
Scientists discover how breast cancer cells spread from blood vessels
09 Feb 2016
Research led by Dr Claus Jørgensen has identified a protein that controls how breast cancer cells spread around the body.
Institute researcher wins share of £1 million to investigate pancreatic cancer
04 Feb 2016
Dr Claus Jørgensen is one of six scientists to have new research projects funded by Pancreatic Cancer Research Fund (PCRF).
Treatment resistance in melanoma
29 Jan 2016
Scientists from our Institute have found that certain melanoma cells change the way they produce energy for growth, offering an insight into drug resistance and a potential way to treat resistant tumours in the clinic.
The Dexter Award recognises outstanding achievements of Tim Somerville
14 Dec 2015
Tim Somerville is the winner of the Institute’s Dexter Award for Young Scientists for 2015.
Cancer Research UK ‘Future Leaders in Cancer Research’ Prize Winner
27 Nov 2015
John Brognard was awarded a prestigious Cancer Research UK ‘Future Leaders in Cancer Research’ prize.
British Association for Cancer Research Translational Award winner
26 Nov 2015
Romina Girotti, a postdoctoral fellow in the Molecular Oncology group, has received a British Association for Cancer Research (BACR) Translational Award
Election to Academia Europaea
23 Nov 2015
Institute Director Professor Richard Marais has been elected to the Academia Europaea.
Leukaemia gene stops blood cells ‘growing up’
24 Sep 2015
Our scientists have identified a gene – FOXC1 – that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukaemia (AML) patients
Melanoma scientist awarded prestigious cancer research award
07 Sep 2015
Dr Romina Girotti, from the Molecular Oncology group, has been awarded the Young Investigator’s Award by ECCO.
One step closer for predictive ‘liquid biopsy’ in cancer patients
16 Aug 2015
Researchers have developed a robust blood test to identify key molecules that help tumour cells produce energy, thereby supporting cancer growth.
Overcoming why a new treatment is resisted by lung cancer
02 Aug 2015
Research suggests how resistance against a new lung cancer treatment might be overcome.
Anonymous patient's leukaemia genetically mapped to give hope to others
14 Jul 2015
Our scientists have genetically mapped the cancer of a leukaemia patient whose disease was resistant to treatment in order to identify a method of personalising therapy for individuals.
State-of-the-art research centre will transform cancer treatment
26 Jun 2015
A new £28.5m research centre that will transform cancer treatment has opened in Manchester.
Professor Dive is elected to the Academy of Medical Sciences
11 May 2015
Professor Caroline Dive has joined the ranks of eminent UK scientists and become a Fellow of the prestigious Academy of Medical Sciences.
Melanoma’s ‘safe haven’ targeted for shut-down
13 Apr 2015
Melanoma cells become drug resistant by using surrounding healthy cells to provide a ‘safe haven’ from treatment.
Consortium signs deal with Basilea to develop resistance-busting cancer drugs
01 Apr 2015
A group of academic organisations and funders has entered an agreement with biopharmaceutical company Basilea Pharmaceutica Ltd. to progress a new family of cancer drugs designed to block several key cancer-causing proteins at once.
Blood test could help bowel cancer patients avoid drug side-effects
25 Mar 2015
Researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy.
Understanding of cell enzyme flipped on its head
09 Mar 2015
Our researchers, working with scientists in California, have found that certain molecules long thought to promote cancer growth, in fact suppress tumours, suggesting that therapeutic approaches should aim to restore, rather than block, their activity.
CRUK Manchester Institute researcher takes her science to Parliament
23 Feb 2015
Romina Girotti is attending Parliament to present her science to a range of politicians and a panel of expert judges, as part of SET for Britain on Monday 9 March.
Grant awarded to present latest technology for personalised medicine in melanoma
11 Feb 2015
Romina Girotti was recently awarded a grant to present at the EACR-OECI Conference on Precision Medicine for Cancer, 1 – 4 March 2015.
Prize for poster on the tumourigenicity of circulating tumour cells in small cell lung cancer
10 Feb 2015
Clinical and Experimental Pharmacology is awarded a poster prize at the British Thoracic Oncology Group 2015 Meeting.
Cell reprogramming offers hope for blood disease treatment
09 Feb 2015
Stem cell researchers have developed a method to create blood cells that perfectly match individual patients, offering a new treatment approach for blood cancers and other diseases.
Cancer research computing to benefit from being ‘up in the cloud’
02 Feb 2015
Computer scientists have proposed a new approach to linking together the wealth of data generated by cancer research
Tumour-blocking role found for cell regulation molecule
12 Jan 2015
Scientists at the Cancer Research UK Manchester Institute have recently explored the role of a protein in regulating tumour development and found that it suppresses liver cancer growth in the lab.
New targeted drugs could treat drug-resistant skin cancer
02 Jan 2015
Researchers have revealed a brand new family of cancer drugs designed to block several key cancer-causing proteins at once could potentially treat incurable skin cancers.
Scientists zero in on how lung cancer spreads
22 Dec 2014
Research led by Dr Angeliki Malliri has shown microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells – meaning they can break loose and spread.
Major makeover for tissue analysis lab will benefit cancer researchers
11 Dec 2014
Our scientists are benefitting from a major makeover of tissue-based research facilities that we can use for ground-breaking research.
£50M CRT Pioneer Fund investment to develop lung cancer drugs at the Cancer Research UK Manchester Institute
21 Nov 2014
The Cancer Research Technology Pioneer Fund announces its collaboration with the Drug Discovery Unit to develop a promising class of drugs called RET inhibitors to treat cancer.
DNA ‘blind spots’ may hide cancer-causing mistakes
14 Nov 2014
Scientists at The Cancer Research UK Manchester Institute have found more than 400 ‘blind spots’ in DNA which could hide cancer-causing gene faults.
Rapid and accurate process will drive forward understanding of cancer biology
07 Nov 2014
Scientists have developed a new method to quickly and more accurately investigate vital cell communication – a process that often goes wrong in cancer.
When cancer meets fashion
20 Oct 2014
Dr Esther Baena teamed up with a Pennsylvanian fashion designer to create a dress showing how prostate cancer spreads in the body.
Society for Melanoma Research award winner
29 Sep 2014
We wish to congratulate Romina Girotti of the Molecular Oncology group who has won a $1000 travel award from the Society for Melanoma Research.
Scientists learn more about rare skin cancer that killed Bob Marley
27 Aug 2014
Professor Richard Marais and his team in Molecular Oncology have discovered that acral melanomas – the rare type of skin cancer that caused reggae musician Bob Marley’s death – are genetically distinct from other more common types of skin cancer.
New tool to probe cancer’s molecular make-up
25 Aug 2014
Dr Claus Jørgensen, head of the Systems Oncology group, together with researchers from the Institute of Cancer Research, have shown how to better identify and measure vital molecules that control cell behaviour.
Yeast studies shed light on cancer cell processes
12 Aug 2014
Professor Iain Hagan and his team in the Cell Division group work on yeast to study fundamental biological processes – potentially giving a greater insight into what goes wrong in cancer.
Our EACR President
08 Aug 2014
Professor Richard Marais is now the President of the European Association of Cancer Research
Yeast cell response to stress may give clues to cancer development
14 Jul 2014
Dr Crispin Miller, head of the RNA Biology group, is investigating how yeast cells respond to environmental stress in order to gain insight into processes that could help our understanding of cancer development.
Cancer Research UK launches visionary new lung cancer centre of excellence
03 Jul 2014
Cancer Research UK has brought together leading researchers from Manchester and London in the creation of a groundbreaking new Lung Cancer Centre of Excellence, launched on 1 July 2014.
Sunscreen Is Not Enough
12 Jun 2014
The Molecular Oncology team have shown that sunscreen cannot be relied upon alone to prevent malignant melanoma, the most deadly form of skin cancer, according to their research published in Nature.
Potential drug for the treatment of Small Cell Lung Cancer
11 Jun 2014
The journal Clinical Cancer Research has recently published work undertaken by the Clinical and Experimental Pharmacology (CEP) group on the potential use of an experimental drug, AZD3965, in the treatment of Small Cell Lung Cancer (SCLC).
New insight into drug resistance in metastatic melanoma
04 Jun 2014
A study by our researchers in the Molecular Oncology group has shown how melanoma drugs can cause the cancer to progress once a patient has stopped responding to treatment.
“Liquid Biopsy” offers new way to track lung cancer
02 Jun 2014
Our scientists have shown how a lung cancer patient’s blood sample could be used to monitor and predict their response to treatment – paving the way for personalised medicine for the disease.
New way to combat drug resistance in melanoma
02 Jun 2014
RAPID RESISTANCE to vemurafenib – a treatment for a type of advanced melanoma, the deadliest form of skin cancer – could be prevented by blocking a druggable family of proteins, according to research published in Nature Communications by the Institute’s scientists.
New protein linked to leukaemia growth
16 May 2014
Our scientists have discovered a molecule that plays a key role in leukaemia, a protein called PIP4K2A that could be a new target in drug development.
Institute appoints new cancer research group leaders
12 Mar 2014
Two new group leaders are set to join the Cancer Research UK Manchester Institute at The University of Manchester – part of the Manchester Cancer Research Centre.
Movember Centre of Excellence opens on 13 February 2014
07 Mar 2014
We are very excited to announce the launch of the Movember Centre of Excellence, in partnership with Prostate Cancer UK, a joint enterprise between the Cancer Research UK Manchester Institute and Queen’s University Belfast
New study gives greater understanding of processes involved in the control of blood cell growth
29 Jan 2014
Scientists at the Cancer Research UK Manchester Institute have gained new insight into a possible treatment target for leukaemia by looking at what makes blood stem cells stop replicating.
Dexter Award 2013
28 Jan 2014
We are delighted to announce that PhD student Eva Barkauskaite, formerly of the DNA Damage Response group, has been selected as the winner of the Cancer Research UK Manchester Institute Dexter Award for Young Scientists for 2013.
Griem Lectureship in Molecular and Cellular Oncology
20 Dec 2013
We are delighted to announce that our Director of the Institute, Professor Richard Marais, has been awarded the second Griem Lectureship in Molecular and Cellular Oncology from University of Chicago Comprehensive Cancer Center (UCCCC), in recognition for his outstanding contribution to the field of melanoma research that has advanced the development of targeted therapies against melanoma.
MRC Grant Success
19 Dec 2013
We wish to warmly congratulate Dr Angeliki Malliri, head of the Cell Signalling Group, for her successful grant application to the Medical Research Council.
Understanding the genetics of melanoma of the eye
19 Dec 2013
The Molecular Oncology group, led by Professor Richard Marais, has performed the first whole genome sequencing of uveal melanoma, a disease that affects the iris and other pigmented parts of the eye.
TRACERx - Cancer Research UK’s largest funding commitment to lung cancer
13 Aug 2013
A new era in lung cancer research has been unveiled in a world-first Cancer Research UK study that will track, in real time, how lung cancers mutate, adapt and develop resistance as patients receive treatment.
New insights into lung cancer genetics
08 Jul 2013
A new efficient screening strategy has been developed that can identify faulty genes in tumour cells that are possible drug targets for the most common form of lung cancer, according to research published in PNAS on 8 July 2013.
Two drugs better than one to treat most deadly skin cancer
18 Mar 2013
Adding lung cancer drugs to targeted melanoma treatment could increase survival for certain patients, according to research published in Cancer Discovery on 11 February 2013.
Senior Investigator Award: Developing Personalised Medicine for Malignant Melanoma
19 Feb 2013
Professor Richard Marais, Director of the Paterson Institute for Cancer Research and head of the Molecular Oncology Group, is a world leader in melanoma research.
The 2012 Pasteur-Weizmann/Servier International Prize
13 Dec 2012
Professor Caroline Dive, Lead of the Clinical and Experimental Pharmacology Group (CEP), has been awarded the 2012 Pasteur-Weizmann/Servier International Prize in recognition of her pioneering studies in the identification of new serum based biomarkers and for the development of non-invasive procedures in the early diagnosis and management of cancer.
Grant Success for Caroline Dive and Ged Brady
12 Dec 2012
Caroline Dive, Ged Brady and Kyaw Aung from the Clinical and Experimental Pharmacology Group (CEP), together with Pancreatic Specialist Oncologists at the Christie Hospital, Juan Valle and Richard Hubner, have recently been awarded substantial financial support by the Pancreatic Cancer Research Fund.
Grant Success for Georges Lacaud
11 Dec 2012
Georges Lacaud, Stem Cell Biology Group Leader, has been awarded significant funding by Leukaemia & Lymphoma Research to undertake a three-year project to identify and characterise genes regulated by MOZ and MOZ-TIF2.
Fellowship Success
20 Jun 2012
Congratulations to Alexia Eliades who has been awarded an EMBO Post-Doctoral Fellowship.
Grants awarded to the Cell Signalling Group
12 Jan 2012
Angeliki Malliri, head of the Cell Signalling Group, has been awarded two research grants.
Poster prize success for Paterson Student
12 Jan 2012
Ahmet Acar from the Stromal-Tumour Interaction Group, led by Dr Akira Orimo, was runner up in the best student poster competition at the recent NCRI conference in Liverpool.
Manchester team picks up Cancer Research UK prize
15 Nov 2011
A team of researchers from Manchester was yesterday awarded the 2011 Cancer Research UK Prize for Translational Cancer Research at the NCRI Cancer Conference in Liverpool.
Caroline Dive Elected to the European Academy of Cancer Sciences
15 Nov 2011
Professor Caroline Dive from the Paterson Institute has recently been elected a Fellow of the European Academy of Cancer Sciences. Hosted under the auspices of ECCO (European CanCer Organisation), the Academy strives for excellence, independence, leadership, diversity and flexibility.
Ivan Ahel Joins the EMBO Young Investigator Programme
07 Nov 2011
Dr Ivan Ahel, a Junior Group Leader at the Paterson Institute, was one of 22 scientists selected to become members of the European Molecular Biology Organisation (EMBO) Young Investigator Programme.
Skin cancer expert to lead Manchester's Paterson Institute
22 Sep 2011
Cancer Research UK and The University of Manchester have appointed Professor Richard Marais to be the next director of the Paterson Institute for Cancer Research in Manchester.

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