Major new funding for our Cancer Research

Investing in Manchester’s Discovery Engine Room

It’s a big year for cancer research in Manchester, as Cancer Research UK is increasing the annual core funding of our Institute to more than £17m a year as of 2026! That’s a 50% increase in support of patient-benefitting research here in the North West.

From the formation of up to eight new research groups here in Manchester, to investment in the latest cutting edge research and computational technologies, the coming years will see incredible expansion in our ability to understand, treat and prevent cancer.

This funding comes from public support, and we are incredibly grateful to each and every Cancer Research UK donor and fundraiser that supports our shared work.

Within this page you can find what this increase in funding means for you, whether you’re our next Research Group Leader, Technologist, or Partner on our research journey.

Growing talent in Manchester

Alongside our expanding set of research groups, we’re welcoming new Institute Affiliates to our Cancer Research UK Manchester Institute Community.

Institute Affiliates split their time between projects at our Institute and those of a close collaborator such as The University of Manchester or The Christie NHS Foundation Trust.

The two newest Institute Affiliates to join us bring new insights, expertise and experience in two of the areas we’ll be expanding in – Immunology and Computational Biology. They are:

Professor Magnus Rattray is Professor of Computational and Systems Biology at the University of Manchester, where his group develops novel computational, statistical and machine learning approaches for the analysis of spatial and single-cell omics, live cell and fixed imaging, and population health data.

He has collaborated closely with colleagues at the CRUK Manchester Institute over the last decade and hopes to deepen these links over the next few years, using data-driven approaches to uncover the mechanisms underlying cancer initiation, progression and treatment.

Dr Jon Lim is a consultant medical oncologist within the advanced immunotherapy and cell therapy (AICT) team at the Christie NHS Foundation Trust. His clinical practice is in caring for adult patients with solid cancer receiving novel immunotherapies and advanced cell therapies within an active clinical trials research portfolio in AICT.

Working with our Institute teams, Jon will bring invaluable expertise to translational research programmes that seek to generate real impact for patients from the latest insights on immunotherapy performance.

Two headshots of Institute scientists Jon Lim and Magnus Rattray
Institute Affiliate researchers Dr Jon Lim (left) and Prof Magnus Rattray (right)

Investing in our Core Facilities

Scientific image labelled 'Spatial-2,' depicting data related to spatial analysis in research
Slide data related to spatial analysis in research at the Cancer Research UK Manchester Institute

The extensive investment in bringing new research talent into our Manchester cancer research ecosystem will be matched with investment in our already world-leading core facilities.

Based on-site in the Paterson Building, our facilities support every stage of the research process, from the preparation of tissue samples in Histology, to the creation of rich datasets in Molecular Biology and Cytometry, to data analysis and processing support in IT and Scientific Computing.

This increase in funding will support investment in cutting edge platforms in areas such as spatial technologies and high performance computing that mean our research teams can study cancer in greater detail than ever before.

The power of partnerships

Everything that we do at the Cancer Research UK Manchester Institute is enabled by the strength of Manchester’s cancer research partnerships.

As part of the Manchester Cancer Research Centre, our Withington Campus sees us alongside the Christie NHS Foundation Trust, the University of Manchester’s Division of Cancer Sciences, and the Cancer Research UK National Biomarker Centre.

In this environment we’re able to collaborate not just with the best research minds and world-leading technologies, but most importantly also with the more than 60,000 patients that are treated at the Christie hospital each year.

This increase in funding will allow us to strengthen these partnerships and collaborations in Manchester, and extend our collective reach into the global cancer research community, as we search together for the next discoveries that will save lives.

The Paterson Building on the Christie Hospital site in Withington, Manchester, with the Oglesby Cancer Research Building, the Proton Beam Centre and the wider Manchester cityscape
The Paterson Building on the Christie Hospital site in Withington, Manchester, with the Oglesby Cancer Research Building, the Proton Beam Centre and the wider Manchester cityscape

The latest from our Cancer Research UK Manchester Institute

Below you can find our latest research publications and news items.

Images of stained cells superimposed with headshot images of Samra Turajlic and Tim Somervaille
Image of skin cancer in ageing humans

Latest from CRUK MI

Cancer Research In the Paterson Building

Find out more about the facilities across the Institute

Two Institute Scientists elected to the Academy of Medical Sciences

We celebrate the recognition Professor Samra Turajlic and Professor Tim Somervaille by a prestigious medical science institution

New publication: Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion

Research explores the role of lipid signalling in cancer behaviour

Cancer Research In the Paterson Building
Two Institute Scientists elected to the Academy of Medical Sciences
New publication: Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion
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https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2

Plasma signals of lung tumor promotion for molecular cancer prevention

25 June 2026

Institute Authors (1)

William Hill

Research Group

Cancer Origins

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https://link.springer.com/article/10.1038/s44319-026-00809-1

PKMYT1 has an important role in the timing and fidelity of chromosome segregation

5 June 2026

Institute Authors (5)

Asma Belbelazi, Charlie Greenaway-Wells, Zoe Edwards, Keren Dawson, Iain Hagan

Research Group

Cell Division

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https://www.nature.com/articles/s42255-026-01514-y

Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion

27 April 2026

Institute Authors (4)

Amaya Virós, Noah Palombo, Charlotte Russell, Claus Jørgensen

Research Group

Skin Cancer & Ageing

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https://www.cell.com/cancer-cell/fulltext/S1535-6108(26)00114-5

Immunometabolic gatekeeping: How tissue metabolism conditions tumor immunity

13 April 2026

Institute Authors (1)

Samra Turajlić

Research Group

Cancer Dynamics

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https://www.nature.com/articles/s41467-026-69964-2

Disruption of tRNA threonylation triggers RIG-I mediated anti-tumour immune response

25 February 2026

Institute Authors (1)

Sylvain Delaunay

Research Group

RNA Dynamics in Cancer

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https://doi.org/10.1038/s44161-025-00740-z

Single-cell profiling reveals three endothelial-to-hematopoietic transitions with divergent isoform expression landscapes

11 November 2025

Institute Authors (6)

Robert Sellers, John Weightman, Wolfgang Breitwieser, Natalia Moncaut, Michael Lie-a-ling, Georges Lacaud

Labs & Facilities

Computational Biology Support, Molecular Biology, Genome Editing and Mouse Models

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Research Group

Stem Cell Biology

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