Key Details
About the role
The Cancer Research UK Manchester Institute (CRUK MI) is seeking exceptional early-career and senior scientists, including clinician scientists, to establish bold and innovative research programmes as independent Group Leaders.
Situated within one of Europe’s largest and most dynamic cancer research ecosystems, successful candidates will join an outstanding collaborative environment spanning the Cancer Research UK Manchester Institute, the Manchester Cancer Research Centre (MCRC), The University of Manchester, the Lydia Becker Institute of Immunology and Inflammation, the MRC Centre of Research Excellence in Exposome Immunology, and The Christie NHS Foundation Trust.
This unique ecosystem integrates fundamental immunology, cancer biology, computational science, experimental medicine and clinical translation, creating exceptional opportunities to pursue high-impact discovery research while accelerating the development of new immunotherapies, biomarkers and advanced cellular and genetic therapies for patients with cancer.
About you
We are seeking applicants with expertise in cancer immunology, including anti-tumour immunity, immunotherapy, inflammation, stromal and immune interactions within the tumour microenvironment, advanced therapeutic approaches, and systems and computational immunology. We particularly welcome ambitious and innovative research programmes that combine technical excellence and interdisciplinary approaches to address fundamental and translational questions in cancer biology and strengthen our internationally recognised research environment in cancer immunology and immuno-oncology.
How to apply
Translation and Clinical Impact in Manchester
A defining strength of Manchester is the close integration of discovery science with clinical research and patient care.
Through partnership with The Christie NHS Foundation Trust, one of Europe’s largest comprehensive cancer centres, successful candidates will have access to exceptional opportunities for translational and clinical research. These include experimental medicine programmes, window-of-opportunity studies, biomarker-led clinical trials, advanced therapy development and early-phase clinical studies.
Manchester provides a uniquely integrated environment for researchers interested in translating discoveries in tumour immunology into novel therapeutic approaches, including cellular therapies, immune engineering, in vivo genetic engineering, immunomodulatory biologics and precision immunotherapy strategies. The close interaction between discovery scientists, clinician scientists, translational researchers and trialists creates an outstanding platform for moving innovative concepts rapidly from laboratory investigation to patient benefit.
Researchers will also benefit from access to major strategic initiatives across the Manchester ecosystem, including:
- MANIFEST, the national Manchester platform for immunotherapy research and innovation.
- RISE, a multidisciplinary programme developing next-generation approaches to reduce immune stress and cytokine release associated with advanced therapies.
- The MRC Centre of Research Excellence in Exposome Immunology, which is establishing internationally leading capabilities for understanding how environmental exposures shape immune function across health and disease.
Together, these initiatives provide unique opportunities to pursue collaborative and interdisciplinary research at scale.
Our experimental base, equipped with the latest pre-clinical testing platforms, located alongside the largest single-site cancer hospital in Europe, and forming part of a powerful Manchester immunology community, is well-placed to be the source of the next great leaps ahead in cancer immunology.
Professor Samra Turajlić
Director, Cancer Research UK Manchester Institute
More information
Benefits
Find out how contributions to the Institute are recognised with a generous benefits package
Wellbeing
Our mission is to promote and enhance wellbeing through the development of a proactive and enabling culture.
Equality, Diversity and Inclusion
Read about our commitment to creating an environment where diversity is celebrated and everyone is treated fairly
Personal Development
To enable you to excel in your role and continue to develop, we offer a variety of training and support opportunities