Welcome to the Cancer Research UK Manchester Institute
World class research from basic through to clinical

BACR/CRUK Joint Meeting

Evolution and Intratumoural Heterogeneity

11th June 2015

Royal Society of Medicine, London

International PhD Student Cancer Conference 2015   See More

The Cancer Research UK Manchester Institute is a leading cancer research institute within The University of Manchester, core funded by Cancer Research UK, the largest independent cancer research organisation in the world.

Research spans the whole spectrum of cancer research, from programmes investigating the molecular and cellular basis of cancer, to those focussed on translational research and the development of therapeutics.  The Institute (previously known as The Paterson Institute for Cancer Research) is based in the Paterson Building which is adjacent to The Christie NHS Foundation Trust.

Our Institute has recently become a partner in the CRUK Centre of Excellence for Lung Cancer and is a key part of the Belfast-Manchester Movember Centre of Excellence for Prostate Cancer.

Our Latest Publications    See More

A PP1-PP2A phosphatase relay controls mitotic progression.
Grallert A, Boke E, Hagting A, Hodgson B, Connolly Y, Griffiths JR, Smith DL, Pines J, Hagan IM.
Nature. 2014 Dec 10. doi: 10.1038/nature14019. [Epub ahead of print]

Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma.
Girotti MR, Lopes F, Preece N, Niculescu-Duvaz D, Zambon A, Davies L, Whittaker S, Saturno G, Viros A, Pedersen M, Suijkerbuijk BM, Menard D, McLeary R, Johnson L, Fish L, Ejiama S, Sanchez-Laorden B, Hohloch J, Carragher N, Macleod K, Ashton G, Marusiak AA, Fusi A, Brognard J, Frame M, Lorigan P, Marais R, Springer C.
Cancer Cell. 2014 Dec 10. pii: S1535-6108(14)00457-7. doi: 10.1016/j.ccell.2014.11.006. [Epub ahead of print]