Selected Publications
Lim KHJ, Giampazolias E, Schulz O, Rogers NC, Wilkins A, Sahai E, Strid J, Reis e Sousa C. (2022)
Loss of secreted gelsolin enhances response to anticancer therapies.
Journal for Immunotherapy of Cancer 10(9): 1-6. PubMed abstract (PMID: 36162919)
Giampazolias E, Schulz O, Lim KHJ, Rogers NC, Chakravarty P, Srinivasan N, Gordon O, Cardoso A, Buck MD, Poirier EZ, Canton J, Zelenay S, Sammicheli S, Moncaut N, Varsani-Brown S, Rosewell I, Reis e Sousa C. (2021)
Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity.
Cell 184(15):4016-4031.e22. PubMed abstract (PMID: 34081922)
Tunbak H, Enriquez-Gasca R, Tie CHC, Gould PA, Mlcochova P, Gupta RK, Fernandes L, Holt J, van der Veen AG, Giampazolias E, Burns KH, Maillard PV & Rowe HM. (2020)
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s.
Nature Communications 11, 5387: 1-15. PubMed abstract (PMID: 33144593)
Minutti CM, Modak RV, Macdonald F, Li F, Smyth DJ, Dorward DA, Blair N, Husovsky C, Muir A, Giampazolias E, Dobie R, Maizels R, Kendall TJ, Griggs DW, Kopf M, Henderson NC, Zaiss DM. (2019)
A macrophage-pericyte axis directs tissue restoration via Amphiregulin-induced TGFβ activation.
Immunity 50: 645-654. PubMed abstract (PMID: 30770250)
Giampazolias E, Tait SW. (2018)
Caspase-independent cell death: an anti-cancer double-whammy.
Cell Cycle 17(3):269-270. PubMed abstract (PMID: 29169278)
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert M, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SW. (2017)
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.
Nature Cell Biology 19(9): 1116-1129. PubMed abstract (PMID: 28846096)
Woodham E, Paul N, Tyrrell B, Spence H, Swaminathan K, Scribner M, Giampazolias E, Hedley A, Clark W, Kage, F, Marston DJ, Hahn KM, Tait, SWG, Larue L, Brakebusch, CH, Insall, RH, Machesky, LM. (2017)
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.
Current Biology 27: 624-637. PubMed abstract (PMID: 28238662)
Lopez J, Bessou M, Riley JS, Giampazolias E, Todt F, Rochegüe T, Oberst A, Green DR, Edlich F, Ichim G, Tait SW. (2016)
Mito-priming as a method to engineer Bcl-2 addiction.
Nature Communications 7, 10538: 1-11. PubMed abstract (PMID: 26833356)
Giampazolias E, Tait SW. (2016)
Mitochondria and the hallmarks of cancer.
FEBS Journal 283(5): 803-14. PubMed abstract (PMID: 26607558)
Ichim G, Lopez J, Ahmed SU, Muthalagu N, Giampazolias E, Delgado ME, Haller M, Riley JS, Mason SM, Athineos D, Parsons MJ, van de Kooij B, Bouchier-Hayes L, Chalmers AJ, Rooswinkel RW, Oberst A, Blyth K, Rehm M, Murphy DJ, Tait SW. (2015)
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.
Molecular Cell 57(5): 860-72. PubMed abstract (PMID: 25702873)