Our Research

Research at the CRUK Manchester Institute spans the whole spectrum of cancer research, from programmes investigating the molecular and cellular basis of cancer, to those focused on translational research and the development of novel therapeutic approaches.  The Institute works in close collaboration with The Christie and is a partner in the Manchester Cancer Research Centre.

Our aim is to gain a greater understanding of the fundamental basis of how cancer develops and apply that knowledge to develop new diagnostic tests, potential treatments and better ways to predict the outcomes.

We have first class translational research facilities to support current activities and develop into new areas such as molecular pathology. One of the laboratories meets Good Clinical Laboratory Practice standards, and this improves our ability to assess clinical samples from early phase trial patients under the strict regulations which are now required.

Our links with industry are also being strengthened, especially in the translational and clinical research areas. For instance, an alliance with AstraZeneca has resulted in joint initiatives in biomarker research and training opportunities.


CRUK Manchester Institute Research Groups


Molecular Oncology
Deputy Director
Clinical and Experimental Pharmacology


Prostate Oncobiology
Transcriptional Networks in Lung Cancer
Systems Oncology
Cell Signalling
Leukaemia Biology
Cancer Inflammation and Immunity
Translational Oncogenomics
Cell Division
Stem Cell Biology
RNA Biology
Drug Discovery

Institute Fellows

Tumour Suppressors
Skin Cancer and Ageing
Cell Plasticity & Epigenetics