Molecular Biology

  • Design targeting strategy
  • Generation of transgenic, targeting vectors and CRISPR-Cas reagents
  • Design of screening strategy
  • Screening founders for targeted modification


  • Pronuclear/cytoplasmic microinjection (CRISPR-Cas, BACs and plasmids)
  • Blastocyst microinjection (for targeted ES cells)

ES Cell Manipulation

  • Grow and expand imported ES cells for blastocyst injection
  • ES cell targeting
  • Karyotyping
  • Genotyping
  • Mycoplasma screening

Other Services

  • Cryopreservation
  • Colony management