Transplantation

Additional cytogenetic features determine outcome in patients allografted for TP53 mutant acute myeloid leukemia

Loke et al show presence of TP53 mutations in acute myeloid leukemia (AML) are associated with an inferior outcome after an allogeneic stem cell transplant.

Posttransplant MRD and T-cell chimerism status predict outcomes in patients who received allografts for AML/MDS

Authors find presence of posttransplant MRD has an adverse prognostic impact on the outcome irrespective of pretransplant MRD in patients with AML/MDS.