CRUKMI logo image CRUKMI logo image




24 Jan 2023
Manchester Experimental Cancer Medicine Centre success in renewal bid.
19 Jan 2023
Keren Dawson wins 2022 Edith Paterson Prize
03 Jan 2023
Dominic Rothwell is our new Deputy Director of the CRUK Manchester Institute Cancer Biomarker Centre.
12 Dec 2022
Tim Somervaille and Luciano Nicosia present new data in collaboration with CellCentric.
28 Oct 2022
The Somervaille lab provides insight into protein interactions on chromatin and the cell differentiation block in Acute Myeloid Leukaemia.
24 Oct 2022
Caroline Dive receives International Society of Liquid Biopsy Lifetime Achievement Award.
19 Oct 2022
digital ECMT win a Greater Manchester Cancer Award for inclusivity in trials project.
05 Oct 2022
Institute scientists discover the immune system can predict patient response to cancer treatment.
08 Aug 2022
Institute scientists reveal non-invasive method for early detection and monitoring of lung cancer patients.
25 Jul 2022
Postdoc Nasir Haider is awarded a Pancreatic Cancer UK Career Foundation Fellowship.
04 Jul 2022
Postdoc Tim Budden wins BACR Chris Marshall Prize for Cell Signalling.
25 May 2022
Researchers from Manchester and Australia outline the health and economic benefits of banning indoor tanning beds.
10 Mar 2022
Institute scientists among first to discover predictive biomarker that improves patient survival.
24 Jan 2022
Blood test brought to the clinic for the first time to help patients with early-stage melanoma.
10 Jan 2022
Our digitalECMT address the challenges of using technology in healthcare.
30 Nov 2021
Find out how our scientists are overcoming the challenges of lung cancer
26 Jul 2021
Amaya Viros wins prestigious Melanoma Research Alliance and Rosetrees Trust Young Investigator Award.
14 Jul 2021
Rob Bristow awarded Association for Radiation Research 2021 Weiss Medal.
03 Jun 2021
Amaya Viros and colleagues show how the female immune system may protect women from developing aggressive skin cancer.
26 May 2021
Santiago Zelenay and team show immunotherapy works better in combination with anti-inflammatory drugs that target COX-2.
17 May 2021
Caroline Springer and Richard Marais successfully reached the development phase of the Alderley Park Oncology Development Programme.
12 May 2021
Amaya Viros and Skin Cancer and Ageing team show how sun exposure degrades collagen in the skin that reduces skin cancer invasion.
01 Feb 2021
Caroline Dive honoured with IASLC Distinguished Service Awards for her contribution to the field of thoracic cancers.
12 Jan 2021
PhD Student Millie Jones set to tutor pupils from underrepresented backgrounds
11 Jan 2021
New research identifies mutations in a rare eye cancer that could be targeted by drugs used to treat skin cancer.
04 Jan 2021
Dexter Award for the Best Young Scientist of 2020 awarded to Wendy Trotter.
01 Jan 2021
At the start of 2021, we welcome Caroline Dive as Interim Director.
09 Nov 2020
This national programme, supported by CRUK and Innovate UK, aims to find and develop innovations to improve cancer diagnosis and treatment.
14 Oct 2020
Iain Hagan and Wendy Trotter develop a new approach to synchronise the cell division cycle of an entire population of human cells in culture.
05 Aug 2020
Bettina Wingelhofer secures John Goldman Fellowship from Leukaemia UK.
07 Jul 2020
PhD student Alex du Feu wins first place in 2020 Bio-Rad Science Writing Competition
19 May 2020
Isabelle Thompson is among many volunteers who are testing patient samples for coronavirus at the Lighthouse Lab at AP.
18 May 2020
Sophie Richardson is among many volunteers who are testing patient samples for coronavirus at the Lighthouse Lab at AP.
15 May 2020
Dominic Rothwell leads volunteers testing patient samples for coronavirus at the Lighthouse Lab at AP
12 May 2020
PhD student Zoe Lee talks to Royal Society about the impact of the lockdown on her research.
07 May 2020
CRUK MI staff work with AP Lighthouse Laboratory to support SARS-CoV-2 testing.
05 May 2020
Our Steve Bagley has produced over 200 head straps to support NHS workers on the frontline.
24 Mar 2020
CRUK Manchester Institute has suspended all non-essential access across our site until further notice.
02 Mar 2020
New Accelerator awarded to the CRUK MI Cancer Biomarker Centre and partners to ‘digitalise’ experimental cancer medicine centres across the UK, Italy and Spain.
24 Jan 2020
The Institute’s Dexter Award 2019 is jointly awarded to Alice Lallo and Mark Williams.
28 Nov 2019
‘Re-Write Cancer’ campaign will help meet the cost of the new £150m cancer research facility to replace the Paterson Building.
25 Nov 2019
Our researchers receive part share of £1.25m from Prostate Cancer UK and the Movember Foundation to expand work in prostate cancer research.
11 Nov 2019
CRUK has appointed Nic Jones as a new Trustee to join the Charity’s Governing Council in January 2020.
08 Oct 2019
Rob Bristow and others identify biomarkers that may predict how a person’s prostate cancer will grow.
07 Oct 2019
Caroline and team show the potential of CTCs identified at surgical resection to predict relapse of lung cancer.
16 Sep 2019
Caroline Dive wins the Heine H. Hansen Lectureship Award for long-standing work in the field of basic sciences
28 Aug 2019
Phase III trial DETECTION funded by CRUK will use circulating tumour DNA to detect early relapse in patients with stage 2 melanoma.
30 May 2019
Ged Brady is awarded Professorship in recognition of his outstanding work in nucleic acid research.
22 Apr 2019
Researchers from CEP have developed a simple blood test that can match cancer patients to clinical trials.
12 Mar 2019
Team led by Caroline Dive and Andrew Hughes invited to submit full application for CRUK’s Accelerator Award.
11 Mar 2019
Daniel White, Senior Scientific Officer in the Clinical and Experimental Pharmacology group, wins the University’s February Ignition Award
25 Feb 2019
Lucas Trucco to receive prestigious AACR-Pezcoller Foundation Scholar-in-Training Award
31 Jan 2019
Our researchers publish a review of ‘cancers of unknown primary’ exploring liquid biopsies in guiding their treatment.
23 Jan 2019
Institute scientists set to benefit from one of the biggest funding grants ever awarded by Cancer Research UK.
14 Jan 2019
Rob Bristow part of landmark pan-cancer study analyses mutation signatures of hypoxia in over 8,000 tumours.
01 Jan 2019
Rebecca Lee wins 2018 Dexter Prize for Young Scientists
30 Dec 2017
Our Deputy Director Professor Caroline Dive has been awarded a CBE in the New Year's Honours list for services to Cancer Research.
17 Dec 2017
SMR announces that their 15th International Congress will be held in Manchester in October 2018
11 Dec 2017
Melanie Galvin is to receive the Andrew Blake Tribute Award for 2018.
28 Nov 2017
Institute Group Leader Claus Jørgensen is one of 329 top researchers to be awarded an ERC Consolidator Grant.
28 Nov 2017
World-leading cancer researcher Nic Jones has been awarded the Medal of Honour.
24 Nov 2017
Alderley Park, the largest bioscience campus in the UK, is to be CRUK Manchester Institute's interim home.
06 Nov 2017
Dr Santiago Zelenay receives Cancer Research UK’s Future Leader Prize at the NCRI Cancer Conference in Liverpool this week.
22 Jun 2017
Professor Caroline Springer, an expert in cancer therapeutics, will join the Institute to lead our Drug Discovery Unit.
20 Jun 2017
Our researchers discover a two-pronged defence against aggressive bowel cancer.
06 Apr 2017
BRU wins Janet Wood Innovation Award for introducing cable tie “swings” to improve welfare.
24 Mar 2017
Scientists from the Institute will receive funding from Cancer Research UK to develop new treatments for pancreatic cancer using a network of clinical trials.
20 Mar 2017
Professor Richard Marais will receive one of the most prestigious European awards for cancer research: the Léopold Griffuel Award in Translational and Clinical Research.
20 Jan 2017
CRT Pioneer Fund will further develop RET inhibitors through a collaboration with our Drug Discovery Unit.
21 Dec 2016
Researchers discover a subset of CTCs express a vascular endothelial cadherin associated with vasculogenic mimicry.
06 Dec 2016
CRUK Manchester Institute has been recognised for helping to further the communication of animal research in the UK.
21 Nov 2016
A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment.
09 Nov 2016
Using blood the study shows how in future tumour evolution could be monitored without invasive biopsies.
03 Oct 2016
Tim Somervaille, researcher and honorary consultant, has been honoured with a professorship from The University of Manchester
13 Sep 2016
Allan Jordan has received a national award from Cancer Research UK in recognition of his outstanding contribution to the cause.
02 Sep 2016
Researchers show how hypoxia in cancer cells can shift protein-coding genes into becoming non-coding ‘dark matter’.
16 Aug 2016
Our scientists explain some of the contradictory behaviour of Rac1.
12 Aug 2016
Dr Amaya Virós wins the Gold Award from LEO Pharma Research Foundation for exceptional contributions to dermatology research.
01 Aug 2016
Our scientists have shown that a pair of proteins involved in the development of blood cells may have different roles to play, with one apparently much more implicated in certain types of leukaemia.
18 Jul 2016
Anne Largeot wins Best Poster Award at the XXI Wilsede “Modern Trends in Human Leukemia and Cancer” meeting.
13 Jul 2016
The Cancer Research UK Manchester Institute will be a partner in a new European Consortium to foster research on metastatic uveal melanoma and identify new treatments for this serious disease.
09 Jul 2016
Cancer experts from around Europe converge on Manchester to share expertise with our world-leading scientists at a special Congress.
04 Jul 2016
Emma Williams was awarded Best Talk Prize at the 10th International PhD Student Cancer Conference.
29 Jun 2016
Professor Caroline Dive will work with a team from the US to radically accelerate progress against cancer, in one of the first international collaborations inspired by US Vice President Joe Biden’s Cancer Moonshot.
27 Jun 2016
Professor Caroline Dive has recently been awarded a prestigious British Pharmaceutical Society prize.
22 May 2016
Our scientists will play a key role in ground-breaking research into the final stages of cancer.
13 May 2016
A breakthrough study sheds light on how cancer cells and normal cells communicate with each other and could open up new approaches to cancer treatment.
02 May 2016
Caroline Dive is a team member shortlisted to develop a method for generating personalised 4D atlases of cancers.
08 Apr 2016
Dr Maria Romina Girotti is one of four exceptional early career researchers honoured in the 2017 Awards.
07 Apr 2016
Our scientists have identified a potential double drug combination against B-cell acute lymphoblastic leukaemia.
22 Mar 2016
Our researchers have identified mutations in lung cancer that are key to tumour growth, offering a new way to differentiate and treat some patients with the disease.
07 Mar 2016
A blood test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing.
10 Feb 2016
Our scientists have explored the role of one particular cell signalling protein in bowel cancer, and found that its mutation promotes tumour growth.
09 Feb 2016
Research led by Dr Claus Jørgensen has identified a protein that controls how breast cancer cells spread around the body.
04 Feb 2016
Dr Claus Jørgensen is one of six scientists to have new research projects funded by Pancreatic Cancer Research Fund (PCRF).
29 Jan 2016
Scientists from our Institute have found that certain melanoma cells change the way they produce energy for growth, offering an insight into drug resistance and a potential way to treat resistant tumours in the clinic.
14 Dec 2015
Tim Somerville is the winner of the Institute’s Dexter Award for Young Scientists for 2015.
27 Nov 2015
John Brognard was awarded a prestigious Cancer Research UK ‘Future Leaders in Cancer Research’ prize.
26 Nov 2015
Romina Girotti, a postdoctoral fellow in the Molecular Oncology group, has received a British Association for Cancer Research (BACR) Translational Award
23 Nov 2015
Institute Director Professor Richard Marais has been elected to the Academia Europaea.
24 Sep 2015
Our scientists have identified a gene – FOXC1 – that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukaemia (AML) patients
07 Sep 2015
Dr Romina Girotti, from the Molecular Oncology group, has been awarded the Young Investigator’s Award by ECCO.
16 Aug 2015
Researchers have developed a robust blood test to identify key molecules that help tumour cells produce energy, thereby supporting cancer growth.
02 Aug 2015
Research suggests how resistance against a new lung cancer treatment might be overcome.
14 Jul 2015
Our scientists have genetically mapped the cancer of a leukaemia patient whose disease was resistant to treatment in order to identify a method of personalising therapy for individuals.
26 Jun 2015
A new £28.5m research centre that will transform cancer treatment has opened in Manchester.
11 May 2015
Professor Caroline Dive has joined the ranks of eminent UK scientists and become a Fellow of the prestigious Academy of Medical Sciences.
13 Apr 2015
Melanoma cells become drug resistant by using surrounding healthy cells to provide a ‘safe haven’ from treatment.
01 Apr 2015
A group of academic organisations and funders has entered an agreement with biopharmaceutical company Basilea Pharmaceutica Ltd. to progress a new family of cancer drugs designed to block several key cancer-causing proteins at once.
25 Mar 2015
Researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy.
09 Mar 2015
Our researchers, working with scientists in California, have found that certain molecules long thought to promote cancer growth, in fact suppress tumours, suggesting that therapeutic approaches should aim to restore, rather than block, their activity.
23 Feb 2015
Romina Girotti is attending Parliament to present her science to a range of politicians and a panel of expert judges, as part of SET for Britain on Monday 9 March.
11 Feb 2015
Romina Girotti was recently awarded a grant to present at the EACR-OECI Conference on Precision Medicine for Cancer, 1 – 4 March 2015.
10 Feb 2015
Clinical and Experimental Pharmacology is awarded a poster prize at the British Thoracic Oncology Group 2015 Meeting.
09 Feb 2015
Stem cell researchers have developed a method to create blood cells that perfectly match individual patients, offering a new treatment approach for blood cancers and other diseases.
02 Feb 2015
Computer scientists have proposed a new approach to linking together the wealth of data generated by cancer research
12 Jan 2015
Scientists at the Cancer Research UK Manchester Institute have recently explored the role of a protein in regulating tumour development and found that it suppresses liver cancer growth in the lab.
02 Jan 2015
Researchers have revealed a brand new family of cancer drugs designed to block several key cancer-causing proteins at once could potentially treat incurable skin cancers.
22 Dec 2014
Research led by Dr Angeliki Malliri has shown microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells – meaning they can break loose and spread.
11 Dec 2014
Our scientists are benefitting from a major makeover of tissue-based research facilities that we can use for ground-breaking research.
21 Nov 2014
The Cancer Research Technology Pioneer Fund announces its collaboration with the Drug Discovery Unit to develop a promising class of drugs called RET inhibitors to treat cancer.
14 Nov 2014
Scientists at The Cancer Research UK Manchester Institute have found more than 400 ‘blind spots’ in DNA which could hide cancer-causing gene faults.
07 Nov 2014
Scientists have developed a new method to quickly and more accurately investigate vital cell communication – a process that often goes wrong in cancer.
20 Oct 2014
Dr Esther Baena teamed up with a Pennsylvanian fashion designer to create a dress showing how prostate cancer spreads in the body.
29 Sep 2014
We wish to congratulate Romina Girotti of the Molecular Oncology group who has won a $1000 travel award from the Society for Melanoma Research.
27 Aug 2014
Professor Richard Marais and his team in Molecular Oncology have discovered that acral melanomas – the rare type of skin cancer that caused reggae musician Bob Marley’s death – are genetically distinct from other more common types of skin cancer.
25 Aug 2014
Dr Claus Jørgensen, head of the Systems Oncology group, together with researchers from the Institute of Cancer Research, have shown how to better identify and measure vital molecules that control cell behaviour.
12 Aug 2014
Professor Iain Hagan and his team in the Cell Division group work on yeast to study fundamental biological processes – potentially giving a greater insight into what goes wrong in cancer.
08 Aug 2014
Professor Richard Marais is now the President of the European Association of Cancer Research
14 Jul 2014
Dr Crispin Miller, head of the RNA Biology group, is investigating how yeast cells respond to environmental stress in order to gain insight into processes that could help our understanding of cancer development.
03 Jul 2014
Cancer Research UK has brought together leading researchers from Manchester and London in the creation of a groundbreaking new Lung Cancer Centre of Excellence, launched on 1 July 2014.
12 Jun 2014
The Molecular Oncology team have shown that sunscreen cannot be relied upon alone to prevent malignant melanoma, the most deadly form of skin cancer, according to their research published in Nature.
11 Jun 2014
The journal Clinical Cancer Research has recently published work undertaken by the Clinical and Experimental Pharmacology (CEP) group on the potential use of an experimental drug, AZD3965, in the treatment of Small Cell Lung Cancer (SCLC).
04 Jun 2014
A study by our researchers in the Molecular Oncology group has shown how melanoma drugs can cause the cancer to progress once a patient has stopped responding to treatment.
02 Jun 2014
Our scientists have shown how a lung cancer patient’s blood sample could be used to monitor and predict their response to treatment – paving the way for personalised medicine for the disease.
02 Jun 2014
RAPID RESISTANCE to vemurafenib – a treatment for a type of advanced melanoma, the deadliest form of skin cancer – could be prevented by blocking a druggable family of proteins, according to research published in Nature Communications by the Institute’s scientists.
16 May 2014
Our scientists have discovered a molecule that plays a key role in leukaemia, a protein called PIP4K2A that could be a new target in drug development.
12 Mar 2014
Two new group leaders are set to join the Cancer Research UK Manchester Institute at The University of Manchester – part of the Manchester Cancer Research Centre.
07 Mar 2014
We are very excited to announce the launch of the Movember Centre of Excellence, in partnership with Prostate Cancer UK, a joint enterprise between the Cancer Research UK Manchester Institute and Queen’s University Belfast
29 Jan 2014
Scientists at the Cancer Research UK Manchester Institute have gained new insight into a possible treatment target for leukaemia by looking at what makes blood stem cells stop replicating.
28 Jan 2014
We are delighted to announce that PhD student Eva Barkauskaite, formerly of the DNA Damage Response group, has been selected as the winner of the Cancer Research UK Manchester Institute Dexter Award for Young Scientists for 2013.
20 Dec 2013
We are delighted to announce that our Director of the Institute, Professor Richard Marais, has been awarded the second Griem Lectureship in Molecular and Cellular Oncology from University of Chicago Comprehensive Cancer Center (UCCCC), in recognition for his outstanding contribution to the field of melanoma research that has advanced the development of targeted therapies against melanoma.
19 Dec 2013
We wish to warmly congratulate Dr Angeliki Malliri, head of the Cell Signalling Group, for her successful grant application to the Medical Research Council.
19 Dec 2013
The Molecular Oncology group, led by Professor Richard Marais, has performed the first whole genome sequencing of uveal melanoma, a disease that affects the iris and other pigmented parts of the eye.
13 Aug 2013
A new era in lung cancer research has been unveiled in a world-first Cancer Research UK study that will track, in real time, how lung cancers mutate, adapt and develop resistance as patients receive treatment.
08 Jul 2013
A new efficient screening strategy has been developed that can identify faulty genes in tumour cells that are possible drug targets for the most common form of lung cancer, according to research published in PNAS on 8 July 2013.
18 Mar 2013
Adding lung cancer drugs to targeted melanoma treatment could increase survival for certain patients, according to research published in Cancer Discovery on 11 February 2013.
19 Feb 2013
Professor Richard Marais, Director of the Paterson Institute for Cancer Research and head of the Molecular Oncology Group, is a world leader in melanoma research.
13 Dec 2012
Professor Caroline Dive, Lead of the Clinical and Experimental Pharmacology Group (CEP), has been awarded the 2012 Pasteur-Weizmann/Servier International Prize in recognition of her pioneering studies in the identification of new serum based biomarkers and for the development of non-invasive procedures in the early diagnosis and management of cancer.
12 Dec 2012
Caroline Dive, Ged Brady and Kyaw Aung from the Clinical and Experimental Pharmacology Group (CEP), together with Pancreatic Specialist Oncologists at the Christie Hospital, Juan Valle and Richard Hubner, have recently been awarded substantial financial support by the Pancreatic Cancer Research Fund.
11 Dec 2012
Georges Lacaud, Stem Cell Biology Group Leader, has been awarded significant funding by Leukaemia & Lymphoma Research to undertake a three-year project to identify and characterise genes regulated by MOZ and MOZ-TIF2.
20 Jun 2012
Congratulations to Alexia Eliades who has been awarded an EMBO Post-Doctoral Fellowship.
12 Jan 2012
Angeliki Malliri, head of the Cell Signalling Group, has been awarded two research grants.
12 Jan 2012
Ahmet Acar from the Stromal-Tumour Interaction Group, led by Dr Akira Orimo, was runner up in the best student poster competition at the recent NCRI conference in Liverpool.
15 Nov 2011
A team of researchers from Manchester was yesterday awarded the 2011 Cancer Research UK Prize for Translational Cancer Research at the NCRI Cancer Conference in Liverpool.
15 Nov 2011
Professor Caroline Dive from the Paterson Institute has recently been elected a Fellow of the European Academy of Cancer Sciences. Hosted under the auspices of ECCO (European CanCer Organisation), the Academy strives for excellence, independence, leadership, diversity and flexibility.
07 Nov 2011
Dr Ivan Ahel, a Junior Group Leader at the Paterson Institute, was one of 22 scientists selected to become members of the European Molecular Biology Organisation (EMBO) Young Investigator Programme.
22 Sep 2011
Cancer Research UK and The University of Manchester have appointed Professor Richard Marais to be the next director of the Paterson Institute for Cancer Research in Manchester.