MENU
NEWS
RESEARCH

WORLD CLASS BASIC, TRANSLATIONAL AND CLINICAL RESEARCH

News

 

First Johann Anton Merck Award winner
13 July 2020
Prof Caroline Dive wins first Johann Anton Merck Award for contributions to preclinical oncology.
 
Science Writing Competition Winner
07 July 2020
PhD student Alex du Feu wins first place in 2020 Bio-Rad Science Writing Competition
 
CRUK MI scientist on the frontline at coronavirus mega-lab
19 May 2020
Isabelle Thompson is among many volunteers who are testing patient samples for coronavirus at the Lighthouse Lab at AP.
 
CRUK MI scientist on the frontline at coronavirus mega-lab
18 May 2020
Sophie Richardson is among many volunteers who are testing patient samples for coronavirus at the Lighthouse Lab at AP.
 
CRUK MI scientist on the frontline at coronavirus mega-lab
15 May 2020
Dominic Rothwell leads volunteers testing patient samples for coronavirus at the Lighthouse Lab at AP
 
CRUK MI PhD student shares experience of COVID-19 lockdown
12 May 2020
PhD student Zoe Lee talks to Royal Society about the impact of the lockdown on her research.
 
How the CRUK Manchester Institute are supporting the national effort in SARS-CoV-2 testing
07 May 2020
CRUK MI staff work with AP Lighthouse Laboratory to support SARS-CoV-2 testing.
 
COVID-19: CRUK MI scientist manufacturing PPE
05 May 2020
Our Steve Bagley has produced over 200 head straps to support NHS workers on the frontline.
 
COVID-19 Response – our measures to help prevent the spread of the virus
24 March 2020
CRUK Manchester Institute has suspended all non-essential access across our site until further notice.
 
New CRUK Accelerator Award for Digital Clinical Trials to UpSMART Experimental Cancer Medicine Centres
02 March 2020
New Accelerator awarded to the CRUK MI Cancer Biomarker Centre and partners to ‘digitalise’ experimental cancer medicine centres across the UK, Italy and Spain.
 
Dexter Award 2019
24 January 2020
The Institute’s Dexter Award 2019 is jointly awarded to Alice Lallo and Mark Williams.
 

News Items From 2019

Re-Write Cancer in Manchester is launched
28 November 2019
‘Re-Write Cancer’ campaign will help meet the cost of the new £150m cancer research facility to replace the Paterson Building.
 
£1.25m Funding to Further Improve Prostate Cancer Research
25 November 2019
Our researchers receive part share of £1.25m from Prostate Cancer UK and the Movember Foundation to expand work in prostate cancer research.
 
European Network for Young Cancer Researchers Launched in Manchester
18 November 2019
The Society of Spanish Researchers in the UK launches its European Network for Young Cancer Researchers
 
Former Institute Director Nic Jones appointed as Cancer Research UK Trustee
11 November 2019
CRUK has appointed Nic Jones as a new Trustee to join the Charity’s Governing Council in January 2020.
 
Multimillion pound boost for Manchester scientists to detect cancer earlier
21 October 2019
The University of Manchester sets bold research ambition to detect the (almost) undetectable as part of international alliance.
 
Institute success at 3Rs poster event
21 October 2019
Our researchers were winners in all three prize categories at this year’s 3Rs poster event.
 
Clues from DNA could predict growth of prostate cancer
08 October 2019
Rob Bristow and others identify biomarkers that may predict how a person’s prostate cancer will grow.
 
Predicting lung cancer’s return at surgery
07 October 2019
Caroline and team show the potential of CTCs identified at surgical resection to predict relapse of lung cancer.
 
Targeting multiple cancer genes could be key to treating leukaemia
02 October 2019
Institute scientists help discover better treatment for deadly blood cancer.
 
Caroline Dive receives Heine H. Hansen Lectureship Award
16 September 2019
Caroline Dive wins the Heine H. Hansen Lectureship Award for long-standing work in the field of basic sciences
 
Phase III trial DETECTION funded
28 August 2019
Phase III trial DETECTION funded by CRUK will use circulating tumour DNA to detect early relapse in patients with stage 2 melanoma.
 
Paterson Redevelopment Project update
22 August 2019
Planning application for the Paterson Redevelopment Project approved by Manchester City Council
 
Professorship announcement
30 May 2019
Ged Brady is awarded Professorship in recognition of his outstanding work in nucleic acid research.
 
Blood samples to help select the right early phase clinical trials for cancer patients
22 April 2019
Researchers from CEP have developed a simple blood test that can match cancer patients to clinical trials.
 
Institute-led team shortlisted for Cancer Research UK Accelerator Award
12 March 2019
Team led by Caroline Dive and Andrew Hughes invited to submit full application for CRUK’s Accelerator Award.
 
Institute scientist wins February Ignition Award
11 March 2019
Daniel White, Senior Scientific Officer in the Clinical and Experimental Pharmacology group, wins the University’s February Ignition Award
 
Institute researcher wins award to attend 2019 AACR Annual Meeting
25 February 2019
Lucas Trucco to receive prestigious AACR-Pezcoller Foundation Scholar-in-Training Award
 
Institute researchers hope to help solve the mystery of cancers with no known origin
31 January 2019
Our researchers publish a review of ‘cancers of unknown primary’ exploring liquid biopsies in guiding their treatment.
 
Institute scientist rallies residents to unite for World Cancer Day
30 January 2019
Habiba Begum from the Drug Discovery Unit is backing Cancer Research UK’s campaign for World Cancer Day
 
Researchers set to receive over £2 million funding from Cancer Research UK
23 January 2019
Institute scientists set to benefit from one of the biggest funding grants ever awarded by Cancer Research UK.
 
Researchers discover common markers of tumour hypoxia across 19 cancer types
14 January 2019
Rob Bristow part of landmark pan-cancer study analyses mutation signatures of hypoxia in over 8,000 tumours.
 
Dexter Prize 2018
01 January 2019
Rebecca Lee wins 2018 Dexter Prize for Young Scientists
 

News Items From 2018

digital Experimental Cancer Medicine Team win Patient Engagement award
10 December 2018
digitalECMT receives the Patient Engagement award at the Microsoft Health & Artificial Intelligence Summit.
 
Institute Professorships announced
03 December 2018
Inaugural lectures of recently promoted Professor Georges Lacaud and Professor Angeliki Malliri were held in October.
 
Exploring cells within cells
13 September 2018
Patricia Muller and colleagues show that a mutant gene is linked to the formation of cell-in-cell structures.
 
Institute Clinical Fellow wins McElwain Prize
07 September 2018
Rebecca Lee has won the Association of Cancer Physicians McElwain translational research prize for “Circulating tumour DNA as a tool to guide clinical decision making in melanoma”.
 
Spatio-temporal regulation of key Rho-family protein is linked to perinuclear actin cap function
08 August 2018
Nature Communications study provides new insights into the perinuclear actin cap and nuclear morphology
 
Honorary appointment for outgoing CEO of CRUK
16 July 2018
Sir Harpal Kumar, the eminent and influential Chief Executive of Cancer Research UK, has been appointed an honorary Chair in Cancer Sciences in the Faculty of Biology, Medicine and Health at The University of Manchester.
 
Distinguished Achievement Award Winners
02 July 2018
Stuart Pepper, Caroline Wilkinson and Kenny Nolan win Team Distinguished Achievement Award
 
Acteria Prize winner
01 July 2018
Eduardo Bonavita wins Acteria Prize for the best PhD thesis in Immunology in Europe
 
Winner of the 2018 BACR Chris Marshall Prize for Cell Signalling
11 June 2018
Zoi Diamantopoulou receives prestigious BACR Chris Marshall Prize for Cell Signalling.
 
CRUK Manchester Institute researcher receives Fulbright Award to the US
16 May 2018
Postdoctoral researcher, Dr Stuart Williamson, receives Fulbright Award to the US
 
Institute Director elected Fellow of the Royal Society
10 May 2018
The Royal Society has granted its prestigious fellowship to Institute Director Professor Richard Marais FRS.
 
Truncation- and motif-based pan-cancer analysis reveals tumour-suppressing kinases
17 April 2018
A kinase domain–focused functional genomic screen reveals loss-of-function mutations in a JNK pathway kinase in gastric cancer.
 
New world-class cancer centre to open in Manchester
11 April 2018
Ambitious, world-class cancer research facility to be built on the site of the Paterson Building.
 
IDEAYA Biosciences and Cancer Research UK Announce Partnership Agreement to Develop Small Molecule Inhibitors of PARG
13 March 2018
IDEAYA Biosciences enters into partnership agreement with CRUK’s Commercial Partnerships Team and the Drug Discovery Unit to develop small molecule inhibitors of PARG.
 
Institute postdoc awarded Kay Kendall Leukaemia Fund Junior Research Fellowship
12 February 2018
Dr Isabel Romero-Camarero has been awarded a prestigious Kay Kendall Leukaemia Fund Junior Research Fellowship, which supports outstanding individuals wishing to pursue research into haematological malignancies.
 
Institute researcher invited to give prestigious conference lecture
30 January 2018
Dr Amaya Virós to deliver the Rising Star Lecture at the 2018 International Investigative Dermatology Meeting.
 

News Items From 2017

Prof Caroline Dive awarded CBE in the New Year's Honours list
30 December 2017
Our Deputy Director Professor Caroline Dive has been awarded a CBE in the New Year's Honours list for services to Cancer Research.
 
Society for Melanoma Research chooses Manchester for 2018 Congress
17 December 2017
SMR announces that their 15th International Congress will be held in Manchester in October 2018
 
3Rs star wins the 2018 Andrew Blake Tribute Award
11 December 2017
Melanie Galvin is to receive the Andrew Blake Tribute Award for 2018.
 
Institute Group Leader to receive €2million ERC funding
28 November 2017
Institute Group Leader Claus Jørgensen is one of 329 top researchers to be awarded an ERC Consolidator Grant.
 
University Medal of Honour for Professor Nic Jones
28 November 2017
World-leading cancer researcher Nic Jones has been awarded the Medal of Honour.
 
CRUK Manchester Institute to set up major base at Alderley Park
24 November 2017
Alderley Park, the largest bioscience campus in the UK, is to be CRUK Manchester Institute's interim home.
 
Institute scientist named as ‘Future Leader’ by Cancer Research UK
06 November 2017
Dr Santiago Zelenay receives Cancer Research UK’s Future Leader Prize at the NCRI Cancer Conference in Liverpool this week.
 
Institute researcher wins prize as part of national team
06 November 2017
Caroline Dive part of the team to win Cancer Research UK’s 2017 Translational Cancer Research Prize
 
Expert in cancer therapeutics to lead Drug Discovery Unit
22 June 2017
Professor Caroline Springer, an expert in cancer therapeutics, will join the Institute to lead our Drug Discovery Unit.
 
New insight into reining in bowel cancer spread
20 June 2017
Our researchers discover a two-pronged defence against aggressive bowel cancer.
 
3Rs award for BRU
06 April 2017
BRU wins Janet Wood Innovation Award for introducing cable tie “swings” to improve welfare.
 
Manchester scientists are to receive £1.2million to help transform pancreatic cancer treatment
24 March 2017
Scientists from the Institute will receive funding from Cancer Research UK to develop new treatments for pancreatic cancer using a network of clinical trials.
 
Institute Director to receive prestigious Léopold Griffuel Award
20 March 2017
Professor Richard Marais will receive one of the most prestigious European awards for cancer research: the Léopold Griffuel Award in Translational and Clinical Research.
 
The CRT Pioneer Fund and Cancer Research UK Manchester Institute nominate cancer drug candidate
20 January 2017
CRT Pioneer Fund will further develop RET inhibitors through a collaboration with our Drug Discovery Unit.
 

News Items From 2016

Pseudo-blood vessels linked to poor survival in lung cancer
21 December 2016
Researchers discover a subset of CTCs express a vascular endothelial cadherin associated with vasculogenic mimicry.
 
Cancer Research UK Manchester Institute wins an Understanding Animal Research Openness Award
06 December 2016
CRUK Manchester Institute has been recognised for helping to further the communication of animal research in the UK.
 
Blood test could predict best treatment for lung cancer
21 November 2016
A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment.
 
Liquid biopsy reveals ‘Jekyll and Hyde’ nature of rare melanoma
09 November 2016
Using blood the study shows how in future tumour evolution could be monitored without invasive biopsies.
 
CRT and the Drug Discovery Unit receive success payment from GlaxoSmithKline for research collaboration
07 October 2016
CRT has received a success payment from GlaxoSmithKline resulting from its collaboration developing molecules targeting cancer epigenetics.
 
Christie consultant made professor
03 October 2016
Tim Somervaille, researcher and honorary consultant, has been honoured with a professorship from The University of Manchester
 
Scientist’s dedication to charity earns national praise
13 September 2016
Allan Jordan has received a national award from Cancer Research UK in recognition of his outstanding contribution to the cause.
 
Exploring how a lack of oxygen gives cancer the evolutionary advantage
02 September 2016
Researchers show how hypoxia in cancer cells can shift protein-coding genes into becoming non-coding ‘dark matter’.
 
Cellular signalling 'tug-of-war' proteins identified
16 August 2016
Our scientists explain some of the contradictory behaviour of Rac1.
 
Gold LEO Pharma Research Foundation Award
12 August 2016
Dr Amaya Virós wins the Gold Award from LEO Pharma Research Foundation for exceptional contributions to dermatology research.
 
Twin blood cell growth proteins are not identical
01 August 2016
Our scientists have shown that a pair of proteins involved in the development of blood cells may have different roles to play, with one apparently much more implicated in certain types of leukaemia.
 
Wilsede Best Poster Award
18 July 2016
Anne Largeot wins Best Poster Award at the XXI Wilsede “Modern Trends in Human Leukemia and Cancer” meeting.
 
Manchester cancer scientists among those to get on their soapboxes
15 July 2016
Soapbox Science is back in Manchester and cancer researchers from the Cancer Research UK Manchester Institute are taking part.
 
New European Consortium launched to fight eye cancer
13 July 2016
The Cancer Research UK Manchester Institute will be a partner in a new European Consortium to foster research on metastatic uveal melanoma and identify new treatments for this serious disease.
 
European cancer scientists converge on Manchester to share latest research
09 July 2016
Cancer experts from around Europe converge on Manchester to share expertise with our world-leading scientists at a special Congress.
 
IPSCC Prize winner
04 July 2016
Emma Williams was awarded Best Talk Prize at the 10th International PhD Student Cancer Conference.
 
Cancer Research UK Manchester Institute joins forces with U.S. ‘Cancer Moonshot’ to develop advanced cancer cell detection technology
29 June 2016
Professor Caroline Dive will work with a team from the US to radically accelerate progress against cancer, in one of the first international collaborations inspired by US Vice President Joe Biden’s Cancer Moonshot.
 
Caroline Dive wins AstraZeneca Prize for Women in Pharmacology
27 June 2016
Professor Caroline Dive has recently been awarded a prestigious British Pharmaceutical Society prize.
 
Our researchers lead the way in cutting-edge research
22 May 2016
Our scientists will play a key role in ground-breaking research into the final stages of cancer.
 
Cancer cells turn healthy cells to the ‘dark side’
13 May 2016
A breakthrough study sheds light on how cancer cells and normal cells communicate with each other and could open up new approaches to cancer treatment.
 
CRUK Grand Challenge five: build a ‘Google Street View’ for cancer shortlisted
02 May 2016
Caroline Dive is a team member shortlisted to develop a method for generating personalised 4D atlases of cancers.
 
Prestigious fellowship for CRUK Manchester Institute clinician scientist
14 April 2016
Dr Amaya Virós, a clinician scientist, has been awarded a Wellcome Trust Intermediate Clinician Scientist Fellowship.
 
Institute postdoctoral scientist honoured in prestigious Biochemical Society Awards
08 April 2016
Dr Maria Romina Girotti is one of four exceptional early career researchers honoured in the 2017 Awards.
 
Scientists identify possible double whammy to attack leukaemia
07 April 2016
Our scientists have identified a potential double drug combination against B-cell acute lymphoblastic leukaemia.
 
Researchers find a genetic new target for most common lung cancer
22 March 2016
Our researchers have identified mutations in lung cancer that are key to tumour growth, offering a new way to differentiate and treat some patients with the disease.
 
Blood test may give early warning of skin cancer relapse
07 March 2016
A blood test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing.
 
Illuminating one dark spot in the genetics of bowel cancer
10 February 2016
Our scientists have explored the role of one particular cell signalling protein in bowel cancer, and found that its mutation promotes tumour growth.
 
Scientists discover how breast cancer cells spread from blood vessels
09 February 2016
Research led by Dr Claus Jørgensen has identified a protein that controls how breast cancer cells spread around the body.
 
Institute researcher wins share of £1 million to investigate pancreatic cancer
04 February 2016
Dr Claus Jørgensen is one of six scientists to have new research projects funded by Pancreatic Cancer Research Fund (PCRF).
 
Treatment resistance in melanoma
29 January 2016
Scientists from our Institute have found that certain melanoma cells change the way they produce energy for growth, offering an insight into drug resistance and a potential way to treat resistant tumours in the clinic.
 

News Items From 2015

The Dexter Award recognises outstanding achievements of Tim Somerville
14 December 2015
Tim Somerville is the winner of the Institute’s Dexter Award for Young Scientists for 2015.
 
Cancer Research UK ‘Future Leaders in Cancer Research’ Prize Winner
27 November 2015
John Brognard was awarded a prestigious Cancer Research UK ‘Future Leaders in Cancer Research’ prize.
 
British Association for Cancer Research Translational Award winner
26 November 2015
Romina Girotti, a postdoctoral fellow in the Molecular Oncology group, has received a British Association for Cancer Research (BACR) Translational Award
 
Election to Academia Europaea
23 November 2015
Institute Director Professor Richard Marais has been elected to the Academia Europaea.
 
Leukaemia gene stops blood cells ‘growing up’
24 September 2015
Our scientists have identified a gene – FOXC1 – that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukaemia (AML) patients
 
Melanoma scientist awarded prestigious cancer research award
07 September 2015
Dr Romina Girotti, from the Molecular Oncology group, has been awarded the Young Investigator’s Award by ECCO.
 
One step closer for predictive ‘liquid biopsy’ in cancer patients
16 August 2015
Researchers have developed a robust blood test to identify key molecules that help tumour cells produce energy, thereby supporting cancer growth.
 
Overcoming why a new treatment is resisted by lung cancer
02 August 2015
Research suggests how resistance against a new lung cancer treatment might be overcome.
 
Anonymous patient's leukaemia genetically mapped to give hope to others
14 July 2015
Our scientists have genetically mapped the cancer of a leukaemia patient whose disease was resistant to treatment in order to identify a method of personalising therapy for individuals.
 
State-of-the-art research centre will transform cancer treatment
26 June 2015
A new £28.5m research centre that will transform cancer treatment has opened in Manchester.
 
Professor Dive is elected to the Academy of Medical Sciences
11 May 2015
Professor Caroline Dive has joined the ranks of eminent UK scientists and become a Fellow of the prestigious Academy of Medical Sciences.
 
Melanoma’s ‘safe haven’ targeted for shut-down
13 April 2015
Melanoma cells become drug resistant by using surrounding healthy cells to provide a ‘safe haven’ from treatment.
 
European consortium to validate blood-based biomarkers for cancer
06 April 2015
Professor Caroline Dive is part of CANCER-ID, a newly formed European consortium funded by the Innovative Medicines Initiative (IMI) aiming to establish standard protocols for clinical validation of blood-based biomarkers.
 
Consortium signs deal with Basilea to develop resistance-busting cancer drugs
01 April 2015
A group of academic organisations and funders has entered an agreement with biopharmaceutical company Basilea Pharmaceutica Ltd. to progress a new family of cancer drugs designed to block several key cancer-causing proteins at once.
 
Blood test could help bowel cancer patients avoid drug side-effects
25 March 2015
Researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy.
 
Caroline Dive receives Manchester International Women’s Day Award
15 March 2015
Caroline Dive wins an International Women’s Day Award in recognition of her pioneering work on circulating biomarkers and the development of minimally invasive biopsies for cancer patients.
 
Understanding of cell enzyme flipped on its head
09 March 2015
Our researchers, working with scientists in California, have found that certain molecules long thought to promote cancer growth, in fact suppress tumours, suggesting that therapeutic approaches should aim to restore, rather than block, their activity.
 
CRUK Manchester Institute researcher takes her science to Parliament
23 February 2015
Romina Girotti is attending Parliament to present her science to a range of politicians and a panel of expert judges, as part of SET for Britain on Monday 9 March.
 
Grant awarded to present latest technology for personalised medicine in melanoma
11 February 2015
Romina Girotti was recently awarded a grant to present at the EACR-OECI Conference on Precision Medicine for Cancer, 1 – 4 March 2015.
 
Prize for poster on the tumourigenicity of circulating tumour cells in small cell lung cancer
10 February 2015
Clinical and Experimental Pharmacology is awarded a poster prize at the British Thoracic Oncology Group 2015 Meeting.
 
Cell reprogramming offers hope for blood disease treatment
09 February 2015
Stem cell researchers have developed a method to create blood cells that perfectly match individual patients, offering a new treatment approach for blood cancers and other diseases.
 
Cancer research computing to benefit from being ‘up in the cloud’
02 February 2015
Computer scientists have proposed a new approach to linking together the wealth of data generated by cancer research
 
Tumour-blocking role found for cell regulation molecule
12 January 2015
Scientists at the Cancer Research UK Manchester Institute have recently explored the role of a protein in regulating tumour development and found that it suppresses liver cancer growth in the lab.
 
New targeted drugs could treat drug-resistant skin cancer
02 January 2015
Researchers have revealed a brand new family of cancer drugs designed to block several key cancer-causing proteins at once could potentially treat incurable skin cancers.
 

News Items From 2014

Scientists zero in on how lung cancer spreads
22 December 2014
Research led by Dr Angeliki Malliri has shown microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells – meaning they can break loose and spread.
 
Major makeover for tissue analysis lab will benefit cancer researchers
11 December 2014
Our scientists are benefitting from a major makeover of tissue-based research facilities that we can use for ground-breaking research.
 
£50M CRT Pioneer Fund investment to develop lung cancer drugs at the Cancer Research UK Manchester Institute
21 November 2014
The Cancer Research Technology Pioneer Fund announces its collaboration with the Drug Discovery Unit to develop a promising class of drugs called RET inhibitors to treat cancer.
 
DNA ‘blind spots’ may hide cancer-causing mistakes
14 November 2014
Scientists at The Cancer Research UK Manchester Institute have found more than 400 ‘blind spots’ in DNA which could hide cancer-causing gene faults.
 
Rapid and accurate process will drive forward understanding of cancer biology
07 November 2014
Scientists have developed a new method to quickly and more accurately investigate vital cell communication – a process that often goes wrong in cancer.
 
When cancer meets fashion
20 October 2014
Dr Esther Baena teamed up with a Pennsylvanian fashion designer to create a dress showing how prostate cancer spreads in the body.
 
Society for Melanoma Research award winner
29 September 2014
We wish to congratulate Romina Girotti of the Molecular Oncology group who has won a $1000 travel award from the Society for Melanoma Research.
 
Scientists learn more about rare skin cancer that killed Bob Marley
27 August 2014
Professor Richard Marais and his team in Molecular Oncology have discovered that acral melanomas – the rare type of skin cancer that caused reggae musician Bob Marley’s death – are genetically distinct from other more common types of skin cancer.
 
New tool to probe cancer’s molecular make-up
25 August 2014
Dr Claus Jørgensen, head of the Systems Oncology group, together with researchers from the Institute of Cancer Research, have shown how to better identify and measure vital molecules that control cell behaviour.
 
Yeast studies shed light on cancer cell processes
12 August 2014
Professor Iain Hagan and his team in the Cell Division group work on yeast to study fundamental biological processes – potentially giving a greater insight into what goes wrong in cancer.
 
Our EACR President
08 August 2014
Professor Richard Marais is now the President of the European Association of Cancer Research
 
Yeast cell response to stress may give clues to cancer development
14 July 2014
Dr Crispin Miller, head of the RNA Biology group, is investigating how yeast cells respond to environmental stress in order to gain insight into processes that could help our understanding of cancer development.
 
Cancer Research UK launches visionary new lung cancer centre of excellence
03 July 2014
Cancer Research UK has brought together leading researchers from Manchester and London in the creation of a groundbreaking new Lung Cancer Centre of Excellence, launched on 1 July 2014.
 
Sunscreen Is Not Enough
12 June 2014
The Molecular Oncology team have shown that sunscreen cannot be relied upon alone to prevent malignant melanoma, the most deadly form of skin cancer, according to their research published in Nature.
 
Potential drug for the treatment of Small Cell Lung Cancer
11 June 2014
The journal Clinical Cancer Research has recently published work undertaken by the Clinical and Experimental Pharmacology (CEP) group on the potential use of an experimental drug, AZD3965, in the treatment of Small Cell Lung Cancer (SCLC).
 
New insight into drug resistance in metastatic melanoma
04 June 2014
A study by our researchers in the Molecular Oncology group has shown how melanoma drugs can cause the cancer to progress once a patient has stopped responding to treatment.
 
“Liquid Biopsy” offers new way to track lung cancer
02 June 2014
Our scientists have shown how a lung cancer patient’s blood sample could be used to monitor and predict their response to treatment – paving the way for personalised medicine for the disease.
 
New way to combat drug resistance in melanoma
02 June 2014
RAPID RESISTANCE to vemurafenib – a treatment for a type of advanced melanoma, the deadliest form of skin cancer – could be prevented by blocking a druggable family of proteins, according to research published in Nature Communications by the Institute’s scientists.
 
New protein linked to leukaemia growth
16 May 2014
Our scientists have discovered a molecule that plays a key role in leukaemia, a protein called PIP4K2A that could be a new target in drug development.
 
Institute appoints new cancer research group leaders
12 March 2014
Two new group leaders are set to join the Cancer Research UK Manchester Institute at The University of Manchester – part of the Manchester Cancer Research Centre.
 
Movember Centre of Excellence opens on 13 February 2014
07 March 2014
We are very excited to announce the launch of the Movember Centre of Excellence, in partnership with Prostate Cancer UK, a joint enterprise between the Cancer Research UK Manchester Institute and Queen’s University Belfast
 
New study gives greater understanding of processes involved in the control of blood cell growth
29 January 2014
Scientists at the Cancer Research UK Manchester Institute have gained new insight into a possible treatment target for leukaemia by looking at what makes blood stem cells stop replicating.
 
Dexter Award 2013
28 January 2014
We are delighted to announce that PhD student Eva Barkauskaite, formerly of the DNA Damage Response group, has been selected as the winner of the Cancer Research UK Manchester Institute Dexter Award for Young Scientists for 2013.
 

News Items From 2013

Griem Lectureship in Molecular and Cellular Oncology
20 December 2013
We are delighted to announce that our Director of the Institute, Professor Richard Marais, has been awarded the second Griem Lectureship in Molecular and Cellular Oncology from University of Chicago Comprehensive Cancer Center (UCCCC), in recognition for his outstanding contribution to the field of melanoma research that has advanced the development of targeted therapies against melanoma.
 
MRC Grant Success
19 December 2013
We wish to warmly congratulate Dr Angeliki Malliri, head of the Cell Signalling Group, for her successful grant application to the Medical Research Council.
 
Understanding the genetics of melanoma of the eye
19 December 2013
The Molecular Oncology group, led by Professor Richard Marais, has performed the first whole genome sequencing of uveal melanoma, a disease that affects the iris and other pigmented parts of the eye.
 
TRACERx - Cancer Research UK’s largest funding commitment to lung cancer
13 August 2013
A new era in lung cancer research has been unveiled in a world-first Cancer Research UK study that will track, in real time, how lung cancers mutate, adapt and develop resistance as patients receive treatment.
 
New insights into lung cancer genetics
08 July 2013
A new efficient screening strategy has been developed that can identify faulty genes in tumour cells that are possible drug targets for the most common form of lung cancer, according to research published in PNAS on 8 July 2013.
 
Two drugs better than one to treat most deadly skin cancer
18 March 2013
Adding lung cancer drugs to targeted melanoma treatment could increase survival for certain patients, according to research published in Cancer Discovery on 11 February 2013.
 
Senior Investigator Award: Developing Personalised Medicine for Malignant Melanoma
19 February 2013
Professor Richard Marais, Director of the Paterson Institute for Cancer Research and head of the Molecular Oncology Group, is a world leader in melanoma research.
 

News Items From 2012

The 2012 Pasteur-Weizmann/Servier International Prize
13 December 2012
Professor Caroline Dive, Lead of the Clinical and Experimental Pharmacology Group (CEP), has been awarded the 2012 Pasteur-Weizmann/Servier International Prize in recognition of her pioneering studies in the identification of new serum based biomarkers and for the development of non-invasive procedures in the early diagnosis and management of cancer.
 
Grant Success for Caroline Dive and Ged Brady
12 December 2012
Caroline Dive, Ged Brady and Kyaw Aung from the Clinical and Experimental Pharmacology Group (CEP), together with Pancreatic Specialist Oncologists at the Christie Hospital, Juan Valle and Richard Hubner, have recently been awarded substantial financial support by the Pancreatic Cancer Research Fund.
 
Grant Success for Georges Lacaud
11 December 2012
Georges Lacaud, Stem Cell Biology Group Leader, has been awarded significant funding by Leukaemia & Lymphoma Research to undertake a three-year project to identify and characterise genes regulated by MOZ and MOZ-TIF2.
 
Fellowship Success
20 June 2012
Congratulations to Alexia Eliades who has been awarded an EMBO Post-Doctoral Fellowship.
 
Grants awarded to the Cell Signalling Group
12 January 2012
Angeliki Malliri, head of the Cell Signalling Group, has been awarded two research grants.
 
Poster prize success for Paterson Student
12 January 2012
Ahmet Acar from the Stromal-Tumour Interaction Group, led by Dr Akira Orimo, was runner up in the best student poster competition at the recent NCRI conference in Liverpool.
 

Related Items


Home

About

Opportunities

Our Research

Services and Technology

Publications

Education

News

Seminars

Contact



Related Links

Cancer Research UK Manchester Centre

Manchester Cancer Research Centre

CRUK Lung Cancer Centre of Excellence



Download our Annual Report