3Rs
3Rs
Institute AWERB chair appointed chair of Animals in Science Committee
Dr Sally Robinson, chair of the CRUK Manchester Institute Animal Welfare and Ethical Review Body (AWERB), has been appointed as chair of the Animals in Science Committee.
Lab-grown lung cancer cells to unlock targeted treatments
Scientists at the Cancer Research Manchester Institute have created a new model of Lung Squamous Cell Carcinoma (LUSC), a common type of lung cancer, to study the development, activity, and vulnerabilities of the disease.
A human model to deconvolve genotype-phenotype causations in lung squamous cell carcinoma
Authors describe a unique model of lung squamous cell carcinoma (LUSC) using genetically modified primary human bronchial basal cells. This strategy constitutes an alternative and patient-relevant system to model LUSC and identify genotype-phenotype correlations relevant for LUSC medicine and early detection.