About Natalia Moncaut
Natalia manages the Genome Editing and Mouse Models Core Facility.
Her work includes designing and deploying the latest genome editing techniques, supporting the process through both in vivo work and in vitro molecular biology. Her in vivo work includes colony management, imports/exports of mouse models, and genotyping strains.
As part of an NC3Rs expert working group she has contributed to a comprehensive resource hub aimed at providing advice on a range of scenarios such as interrupted experiments and reduced colony size. She has developed robust approaches to sustainable cryopreservation of mouse colonies which are contributing the refinement and reduction in animal use.
Interests
- Novel genome editing techniques
- Cryopreservation and colony management
- Molecular Biology
Publications
- Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
- The impact of COVID-19 lockdowns on the genetic integrity of your mouse colonies
- Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation
- Sharing and archiving of GA mice
Careers that have a lasting impact on cancer research and patient care
We are always on the lookout for talented and motivated people to join us. Whether your background is in biological or chemical sciences, mathematics or finance, computer science or logistics, use the links below to see roles across the Institute in our core facilities, operations teams, research groups, and studentships within our exceptional graduate programme.