Publications

Zelenay S*, van der Veen AG, Böttcher JP, Snelgrove KJ, Rogers N, Acton SE, Chakravarty P, Girotti, MR, Marais R, Quezada SA, Sahai E, and Reis e Sousa C*. 2015. Cyclooxygenase-dependent tumor growth through evasion of immunity. Cell 162, 1–14.*Corresponding authors

Helft J, Böttcher J, Chakravarty P, Zelenay S, Huotari J, Schraml BU, Goubau D, and Reis e Sousa C. 2015. GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells. Immunity 42, 1197–1211.

van Blijswijk J, Schraml BU, Rogers NC, Whitney PG, Zelenay S, et al. 2015. Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells. J Immunol 194(1):307–15.

Murillo MM, Zelenay S, Nye E, Castellano E, Lassailly F, et al. 2014. RAS interaction with PI3K p110α is required for tumor-induced angiogenesis. J Clin Invest 124(8):3601–11.

Schraml BU, van Blijswijk J, Zelenay S, Whitney PG, Filby A, Acton SE, Rogers NC, Moncaut N, Carvajal JJ, and Reis e Sousa C. 2013. Genetic Tracing via DNGR-1 Expression History Defines Dendritic Cells as a Hematopoietic Lineage. Cell 154(4):843–858.

Zelenay S and Reis e Sousa C. 2013. Adaptive immunity after cell death. Trends Immunol 34(7):329–335.

Paiva RS, Lino AC, Bergman M-L, Caramalho I, Sousa AE, Zelenay S, and Demengeot J. 2013. Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery. Proc Natl Acad Sci USA 110(16):6494–6499.

Zelenay S, Keller AM, Whitney PG, Schraml BU, Deddouche S, Rogers NC, Schulz O, Sancho D, and Reis e Sousa C. 2012. The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice. J Clin Invest 122(5):1615–1627.

Ahrens S, Zelenay S, Sancho D, Hanč P, Kjær S, Feest C, Fletcher G, et al. 2012. F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells. Immunity 36(4):635–645.

Mourão-Sá D, Robinson MJ, Zelenay S, Sancho D, Chakravarty P, Larsen R, Plantinga M, et al. 2011. CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses. Eur J Immunol 41(10):3040–3053.

Caramalho I, Rodrigues-Duarte L, Perez A, Zelenay S, Penha-Gonçalves C, and Demengeot J. 2011. Regulatory T cells contribute to diabetes protection in lipopolysaccharide-treated non-obese diabetic mice. Scand J Immunol 74(6):585–595.

Zelenay S*, Bergman M-L, Paiva RS, Lino AC, Martins AC, Duarte JH, Moraes Fontes MF, Bilate AM, Lafaille JJ, and Demengeot J. 2010. Cutting edge: Intrathymic differentiation of adaptive Foxp3+ regulatory T cells upon peripheral proinflammatory immunization. J Immunol 185(7):3829–3833.  *Corresponding author.

Poulin LF, Salio M, Griessinger E, Anjos-Afonso F, Craciun L, Chen J-L, Keller AM, Joffre O, Zelenay S, Nye E, et al. 2010. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J Exp Med 207(6):1261–1271.

Joffre OP, Sancho D, Zelenay S, Keller AM, and Reis e Sousa C. 2010. Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A. Eur J Immunol 40(5):1255–1265.

Moraes-Fontes MF, Rebelo M, Caramalho I, Zelenay S, Bergman M-L, Coutinho A, and Demengeot J. 2009. Steroid treatments in mice do not alter the number and function of regulatory T cells, but amplify cyclophosphamide-induced autoimmune disease. J Autoimmun 33(2):109–120.

Duarte JH, Zelenay S, Bergman M-L, Martins AC, and Demengeot J. 2009. Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions. Eur J Immunol 39(4):948–955.

Zelenay S, Moraes Fontes MF, Fesel C, Demengeot J, and Coutinho A. 2007. Physiopathology of natural auto-antibodies: the case for regulation. J Autoimmun 29(4):229–235.

Zelenay S, Chora A, Soares MP, and Demengeot J. 2007. Heme oxygenase-1 is not required for mouse regulatory T cell development and function. Int Immunol 19(1):11–18.

Zelenay S and Demengeot J. 2006. Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells". J Immunol 177(4):2036–7– author reply 2037–8.

Demengeot J, Zelenay S, Moraes-Fontes MF, Caramalho I, and Coutinho A. 2006. Regulatory T cells in microbial infection. Springer Semin Immunopathol 28(1):41–50.

Zelenay S, Lopes-Carvalho T, Caramalho I, Moraes-Fontes MF, Rebelo M, and Demengeot J. 2005. Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion. Proc Natl Acad Sci USA 102(11):4091–4096.

Zelenay S, Elías F, and Fló J. 2003. Immunostimulatory effects of plasmid DNA and synthetic oligodeoxynucleotides. Eur J Immunol 33(5):1382–1392.

Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, and Demengeot J. 2003. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 197(4):403–411.