Publications

Mass Spectral Enhanced Detection of Ubls Using SWATH Acquisition: MEDUSA—Simultaneous Quantification of SUMO and Ubiquitin-Derived Isopeptides
John R Griffiths, Navin Chicooree, Yvonne Connolly, Milla Neffling, Catherine S Lane, Thomas Knapman & Duncan L Smith
J.Am.Soc. Mass Spectrom. (2014) DOI: 10.1007/s13361-014-0835-x Epub 2014 Feb 19 

Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides
Chicooree N, Griffiths JR, Connolly Y,  Smith DL.
Rapid Commun Mass Spectrom. 2013 In press 27:1-7. doi: 10.1002/rcm.6670.

Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection.
Weekes MP, Tan SY, Poole E, Talbot S, Antrobus R, Smith DL, Montag C, Gygi SP, Sinclair JH, Lehner PJ.
Science. 2013 Apr 12;340(6129):199-202. doi: 10.1126/science.

Application of the CIRAD mass spectrometry approach for lysine acetylation site discovery.
Evans CA, Ow SY, Smith DL, Corfe BM, Wright PC.
Methods Mol Biol. 2013;981:13-23. doi: 10.1007/978-1-62703-305-3_2.

Enhanced detection of ubiquitin isopeptides using reductive methylation.
Chicooree N, Connolly Y, Tan CT, Malliri A, Li Y, Smith DL, Griffiths JR.
J Am Soc Mass Spectrom. 2013 Mar;24(3):421-30. doi: 10.1007/s13361-012-0538-0. Epub 2013 Jan 30.

Removal of centrosomal PP1 by NIMA kinase unlocks the MPF feedback loop to promote mitotic commitment in S. pombe.
Grallert A, Chan KY, Alonso-Nuñez ML, Madrid M, Biswas A, Alvarez-Tabarés I, Connolly Y, Tanaka K, Robertson A, Ortiz JM, Smith DL, Hagan IM.
Curr Biol. 2013 Feb 4;23(3):213-22. doi: 10.1016/j.cub.2012.12.039. Epub 2013 Jan 17.

A novel approach to the analysis of SUMOylation with the independent use of trypsin and elastase digestion followed by database searching utilising consecutive residue addition to lysine.
Chicooree N, Griffiths JR, Connolly Y, Tan CT, Malliri A, Eyers CE, Smith DL.
Rapid Commun Mass Spectrom. 2013 Jan 15;27(1):127-34. doi: 10.1002/rcm.6425.

The S. pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1.
Grallert A, Connolly Y, Smith DL, Simanis V, Hagan IM.
Nat Cell Biol. 2012 Jun 10;14(7):738-45. doi: 10.1038/ncb2514.

An insight into iTRAQ: where do we stand now?
Evans C, Noirel J, Ow SY, Salim M, Pereira-Medrano AG, Couto N, Pandhal J, Smith D, Pham TK, Karunakaran E, Zou X, Biggs CA, Wright PC.
Anal Bioanal Chem. 2012 Sep;404(4):1011-27. doi: 10.1007/s00216-012-5918-6. Epub 2012 Mar 27.
PMID: 22451173 [PubMed - in process]

Transient structure associated with the spindle pole body directs meiotic microtubule reorganization in S. pombe.
Funaya C, Samarasinghe S, Pruggnaller S, Ohta M, Connolly Y, Müller J, Murakami H, Grallert A, Yamamoto M, Smith D, Antony C, Tanaka K.
Curr Biol. 2012 Apr 10;22(7):562-74. Epub 2012 Mar 15.
PMID: 22425159 [PubMed - indexed for MEDLINE]

The utility of porous graphitic carbon as a stationary phase in proteomics workflows: Two-dimensional chromatography of complex peptide samples.
Griffiths JR, Perkins S, Connolly Y, Zhang L, Holland M, Barattini V, Pereira L, Edge A, Ritchie H, Smith DL.
J Chromatogr A. 2012 Jan 13. [Epub ahead of print]
PMID: 22326183 [PubMed - as supplied by publisher]

Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6.
Weekes MP, Antrobus R, Talbot S, Hör S, Simecek N, Smith DL, Bloor S, Randow F, Lehner PJ.
J Proteome Res. 2012 Feb 7. [Epub ahead of print]
PMID: 22292497 [PubMed - as supplied by publisher]