Key Details
About the role
We are seeking a Postdoctoral Fellow to work on two landmark studies of cancer evolution in kidney cancer: TRACERx Renal 300 (Tx300) and PEACE (Posthumous Evaluation of Advanced Cancer Environment). Together, these datasets span the full arc of ccRCC disease, from surgical resection of primary tumours through to the metastatic landscape captured postmortem and offer a rare opportunity to study kidney cancer evolution at an unprecedented depth and scale.
The project sits at the intersection of cancer biology and computational analysis. We are looking for someone with genuine biological curiosity and strong quantitative instincts. We value scientific judgement, a drive to understand cancer biology, and sufficient coding experience to work effectively with genomic datasets.
The Cancer Dynamics lab operates across the Cancer Research UK Manchester Institute and the Francis Crick Institute. The role will be based in Manchester with a visiting scientist status at the Crick taking advantage of both research communities.
About you
You should have a PhD in cancer biology molecular biology, genomics, bioinformatics or a related field along with a working knowledge of cancer genomics concepts: somatic mutation, copy number alteration, clonal evolution, phylogenetic reconstruction, tumour heterogeneity. You will have demonstrable experience of scripting in R and/or Python for biological data analysis and the ability to work with large multi-sample genomic datasets and navigate standard genomic file formats and tooling. Prior experience with cancer somatic genomic analyses (e.g. mutation calling, copy number, phylogenetics) would be an advantage.
More information
How to apply
To apply for this position please complete the online application via ‘Apply Now’. Please ensure you detail the names of three referees and ensure you submit your application before 20 September 2026.
For any informal enquiries about this post, please contact Prof Samra Turajlić: samra.turajllic@cruk.manchester.ac.uk
Please note this vacancy will close for applications at 18:00 hours on the closing date specified.
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