Selected Publications
Chastney MR, Lawless C, Humphries JD, Warwood S, Jones MC, Knight D, Jorgensen C, Humphries MJ. (2020)
Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation.
Journal of Cell Biology 219(8):e202003038. PubMed abstract
Kershaw S, Morgan DJ, Boyd J, Spiller DG, Kitchen G, Zindy E, Iqbal M, Rattray M, Sanderson CM, Brass A, Jorgensen C, Hussell T, Matthews LC, Ray DW. (2020)
Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway.
Journal of Cell Science 133(11):jcs242842. PubMed abstract
Tape CJ, Jørgensen C. (2017)
Cell-specific labeling for analyzing bidirectional signaling by mass spectrometry.
Methods in Molecular Biology 1636:219-234. PubMed abstract
Tape CJ, Ling S, Dimitriadi M, McMahon KM, Worboys JD, Leong HS, Norrie IC, Miller CJ, Poulogiannis G, Lauffenburger DA, Jørgensen C. (2016)
Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation.
Cell 165(4) 910-920. PubMed abstract
Locard-Paulet M, Lim L, Veluscek G, McMahon K, Sinclair J, van Weverwijk A, Worboys JD, Yuan Y, Isacke CM, Jørgensen C. (2016)
Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration.
Science Signaling 9(414):ra15. PubMed abstract
So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K. (2015)
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
Science Signaling 8(371):rs3. PubMed abstract
Tape CJ, Worboys JD, Sinclair J, Gourlay R, Vogt J, McMahon KM, Trost M, Lauffenburger DA, Lamont DJ, Jørgensen C. (2014)
Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.
Analytical Chemistry 86(20):10296-302. PubMed abstract
Worboys JD, Sinclair J, Yuan Y, Jørgensen C. (2014)
Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome.
Nature Methods 11(10):1041-4. PubMed abstract
Tape CJ, Norrie IC, Worboys JD, Lim L, Lauffenburger DA, Jørgensen C. (2014)
Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture.
Molecular & Cellular Proteomics 13(7):1866-76. PubMed abstract
Jørgensen C, Sherman A, Chen GI, Pasculescu A, Poliakov A, Hsiung M, Larsen B, Wilkinson DG, Linding R, Pawson T. (2009)
Cell-specific information processing in segregating populations of Eph receptor-ephrin-expressing cells.
Science 326(5959):1502-9. PubMed abstract