Overview
As an Institute we pride ourselves on being as much a community as a workplace. We are proud to share our successes, both inside and outside of the lab with our supporters, friends, and our wide network of collaborators.
Our newsletters contain details of our recent publications, fundraising efforts, new starters, events and more, and gives an insight into the working life of our staff and students.
The latest edition features our move to the new Paterson Building, welcomes new group leader Evangelos Giampazolias, as well as quinquennial review success for Deputy Director Claus Jorgensen plus much more.
As an Institute we pride ourselves on being as much a community as a workplace. We are proud to share our successes, both inside and outside of the lab with our supporters, friends, and our wide network of collaborators.
Our newsletters contain details of our recent publications, fundraising efforts, new starters, events and more, and gives an insight into the working life of our staff and students.
The latest edition features our move to the new Paterson Building, welcomes new group leader Evangelos Giampazolias, as well as quinquennial review success for Deputy Director Claus Jorgensen plus much more.
Scientific Publications
https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-24-1224/766638/Glucocorticoids-Unleash-Immune-dependent-Melanoma
Glucocorticoids Unleash Immune-dependent Melanoma Control through Inhibition of the GARP/TGF β Axis
15 October 2025
Institute Authors (12)
Charles Earnshaw, Poppy Dunn, Shih-Chieh Chiang, Maria Koufaki, Massimo Russo, Kimberley Hockenhull, Erin Richardson, Anna Pidoux, Alex Baker, Richard Reeves, Robert Sellers, Sudhakar Sahoo
Labs & Facilities
Computational Biology Support, Visualisation, Irradiation and Analysis
Research Group
Cancer Inflammation and Immunity
15 October 2025
/wp-content/uploads/2025/09/Annual_Report_2024.pdf
2024 Annual Report
23 September 2025
23 September 2025
https://doi.org/10.1182/blood.2024028033
An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis
4 September 2025
Institute Authors (1)
Justin Loke
Research Group
Myeloid Cancer Biology
4 September 2025
https://doi.org/10.1038/s41467-024-49692-1
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
15 July 2025
Institute Authors (1)
Samra Turajlić
Research Group
Cancer Dynamics
15 July 2025
https://doi.org/10.1038/s41420-025-02582-x
Mutant p53 induces SH3BGRL expression to promote cell engulfment
1 July 2025
Institute Authors (5)
Garry Ashton, John Weightman, Wolfgang Breitwieser, Sudhakar Sahoo, Antonia Banyard
Labs & Facilities
Computational Biology Support, Mass and Flow Cytometry, Molecular Biology
1 July 2025
https://doi.org/10.1016/j.celrep.2025.115603
Functional characterisation of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer
27 May 2025
Institute Authors (2)
Caroline Dive, Kathryn Simpson
Research Group
Small Cell Lung Cancer Biology
27 May 2025