Overview
As an Institute we pride ourselves on being as much a community as a workplace. We are proud to share our successes, both inside and outside of the lab with our supporters, friends, and our wide network of collaborators.
Our newsletters contain details of our recent publications, fundraising efforts, new starters, events and more, and gives an insight into the working life of our staff and students.
The latest edition features our move to the new Paterson Building, welcomes new group leader Evangelos Giampazolias, as well as quinquennial review success for Deputy Director Claus Jorgensen plus much more.
As an Institute we pride ourselves on being as much a community as a workplace. We are proud to share our successes, both inside and outside of the lab with our supporters, friends, and our wide network of collaborators.
Our newsletters contain details of our recent publications, fundraising efforts, new starters, events and more, and gives an insight into the working life of our staff and students.
The latest edition features our move to the new Paterson Building, welcomes new group leader Evangelos Giampazolias, as well as quinquennial review success for Deputy Director Claus Jorgensen plus much more.
Scientific Publications
https://doi.org/10.1186/s12943-024-02157-x
The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer
12 November 2024
Institute Authors (1)
Amaya Viros
Labs & Facilities
Genome Editing and Mouse Models
Research Group
Skin Cancer & Ageing
12 November 2024
https://doi.org/10.1186/s13045-024-01610-0
The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency
8 October 2024
Institute Authors (6)
Georges Lacaud, Mathew Sheridan, Michael Lie-a-ling, Liam Clayfield, Jessica Whittle, Jingru Xu
Research Group
Stem Cell Biology
8 October 2024
/wp-content/uploads/2024/11/Annual-Report-2023.pdf
2023 Annual Report
13 September 2024
13 September 2024
https://doi.org/10.1126/science.adh7954
Vitamin D regulates microbiome-dependent cancer immunity
25 April 2024
Institute Authors (1)
Evangelos Giampazolias
Research Group
Cancer Immunosurveillance
25 April 2024
https://doi.org/10.1038/s41684-024-01363-w
Streamlining mouse genome editing by integrating AAV repair template delivery and CRISPR-Cas electroporation
10 April 2024
Institute Authors (1)
Natalia Moncaut
Labs & Facilities
Genome Editing and Mouse Models
10 April 2024
https://www.biorxiv.org/content/10.1101/2023.12.13.568969v1
A novel human model to deconvolve cell-intrinsic phenotypes of genetically dysregulated pathways in lung squamous cell carcinoma
14 December 2023
Institute Authors (3)
Carlos Lopez-Garcia, Caroline Dive, Anthony Oojageer
Research Group
Translational Lung Cancer Biology
14 December 2023