Overview
As an Institute we pride ourselves on being as much a community as a workplace. We are proud to share our successes, both inside and outside of the lab with our supporters, friends, and our wide network of collaborators.
Our newsletters contain details of our recent publications, fundraising efforts, new starters, events and more, and gives an insight into the working life of our staff and students.
The latest edition features our move to the new Paterson Building, welcomes new group leader Evangelos Giampazolias, as well as quinquennial review success for Deputy Director Claus Jorgensen plus much more.
As an Institute we pride ourselves on being as much a community as a workplace. We are proud to share our successes, both inside and outside of the lab with our supporters, friends, and our wide network of collaborators.
Our newsletters contain details of our recent publications, fundraising efforts, new starters, events and more, and gives an insight into the working life of our staff and students.
The latest edition features our move to the new Paterson Building, welcomes new group leader Evangelos Giampazolias, as well as quinquennial review success for Deputy Director Claus Jorgensen plus much more.
Scientific Publications
https://doi.org/10.1038/s41420-025-02582-x
Mutant p53 induces SH3BGRL expression to promote cell engulfment
1 July 2025
Institute Authors (5)
Garry Ashton, John Weightman, Wolfgang Breitwieser, Sudhakar Sahoo, Antonia Banyard
Labs & Facilities
Computational Biology Support, Flow Cytometry, Molecular Biology
1 July 2025
https://doi.org/10.1016/j.celrep.2025.115603
Functional characterisation of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer
27 May 2025
Institute Authors (2)
Caroline Dive, Kathryn Simpson
Research Group
Small Cell Lung Cancer Biology
27 May 2025
https://doi.org/10.1016/j.ccell.2025.04.001
Stromal lipid species dictate melanoma metastasis and tropism
24 April 2025
Institute Authors (5)
Amaya Viros, Duncan Smith, Garry Ashton, Alex Baker, Tim Somervaille
Labs & Facilities
Biological Mass Spectrometry, Histology, Visualisation, Irradiation and Analysis
Research Group
Skin Cancer & Ageing
24 April 2025
https://doi.org/10.1038/s41467-025-58343-y
A human model to deconvolve genotype-phenotype causations in lung squamous cell carcinoma
4 April 2025
Institute Authors (4)
Carlos Lopez-Garcia, Robert Sellers, Sudhakar Sahoo, Caroline Dive
Labs & Facilities
Computational Biology Support
Research Group
Translational Lung Cancer Biology
4 April 2025
https://doi.org/10.1186/s12943-024-02157-x
The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer
12 November 2024
Institute Authors (1)
Amaya Viros
Labs & Facilities
Genome Editing and Mouse Models
Research Group
Skin Cancer & Ageing
12 November 2024
https://doi.org/10.1186/s13045-024-01610-0
The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency
8 October 2024
Institute Authors (6)
Georges Lacaud, Mathew Sheridan, Michael Lie-a-ling, Liam Clayfield, Jessica Whittle, Jingru Xu
Research Group
Stem Cell Biology
8 October 2024