Overview
Our annual Scientific Reports detail the activities of each research group, describing their publications and research projects for the year. It also contains information about technical and operational activities and our funding streams.
The latest Scientific Report highlights an incredible year of growth for the Institute and many research successes. We welcomed a new Director, Samra Turajlić to the Institute, and saw the establishment of three new independent research groups.
Major research findings were released as an impressive collection of scientific publications. These include investigations on the reasons for increased melanoma aggression in older patients, the pathways of blood formation in embryos that could help us generate fully functional blood stem cells in the lab, and the effectiveness of topical therapies to overcome immunotherapy resistance and restore anti-tumour immunity.
Find the stories from each of our lab growths from a year of advancement in the full report below.
Annual Report 2025
2025 Annual Report
11 November 2026
11 November 2026
https://www.sciencedirect.com/science/article/pii/S2666634026003387?via%3Dihub
Bacteria inside kidney tumors associate with myeloid inflammation and disease progression: A TRACERx Renal study
23 October 2026
Institute Authors (1)
Samra Turajlić
Research Group
Cancer Dynamics
23 October 2026
https://royalsocietypublishing.org/rsob/article/16/8/260089/482862/CDK1-Cyclin-B-mediated-phosphorylation-of-PP2A-B56
CDK1-Cyclin B mediated phosphorylation of PP2A-B56 on B56Par1.T73T75 controls mitotic entry timing and Schizosaccharomyces pombe cell size
19 August 2026
Institute Authors (3)
Lenka Halova, Duncan Smith, Iain Hagan
Labs & Facilities
Biological Mass Spectrometry
Research Group
Cell Division
19 August 2026
https://www.cell.com/immunity/fulltext/S1074-7613(26)00278-5
CCR7+ activated dendritic cells are essential for spontaneous and immunotherapy-driven anti-tumor immunity
4 August 2026
Institute Authors (10)
Erin Richardson, Shih-Chieh Chiang, Massimo Russo, Charles Earnshaw, Anna Pidoux, Poppy Dunn, Sudhakar Sahoo, Antonia Banyard, Natalia Moncaut, Santiago Zelenay
Labs & Facilities
BRU Experimental Team, Computational Biology Support, Genome Editing and Mouse Models, Mass and Flow Cytometry, Transgenic Breeding Team
Research Group
Cancer Inflammation and Immunity
4 August 2026
https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2
Plasma signals of lung tumor promotion for molecular cancer prevention
25 June 2026
Institute Authors (1)
William Hill
Research Group
Cancer Origins
25 June 2026
https://link.springer.com/article/10.1038/s44319-026-00809-1
PKMYT1 has an important role in the timing and fidelity of chromosome segregation
5 June 2026
Institute Authors (6)
Asma Belbelazi, Charlie Greenaway-Wells, Zoe Edwards, Wendy Trotter, Keren Dawson, Iain Hagan
Research Group
Cell Division
5 June 2026



