2024 Annual Report

/wp-content/uploads/2025/09/Annual_Report_2024.pdf 23rd September 2025

Overview

Our annual Scientific Reports detail the activities of each research group, describing their publications and research projects for the year. It also contains information about technical and operational activities and our funding streams.

The latest Scientific Report highlighted how the Institute became fully settled and positioned to maximise the potential of being based on the site of the Christie NHS Foundation Trust with a wealth of opportunities to collaborate and drive transformational cancer research. We also celebrated the formal opening of the Paterson Building in July with special guests and all our colleagues and contributors.

Scientific Publications

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https://royalsocietypublishing.org/rsob/article/16/8/260089/482862/CDK1-Cyclin-B-mediated-phosphorylation-of-PP2A-B56

CDK1-Cyclin B mediated phosphorylation of PP2A-B56 on B56Par1.T73T75 controls mitotic entry timing and Schizosaccharomyces pombe cell size

19 August 2026

Institute Authors (3)

Lenka Halova, Duncan Smith, Iain Hagan

Labs & Facilities

Biological Mass Spectrometry

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Research Group

Cell Division

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https://www.cell.com/immunity/fulltext/S1074-7613(26)00278-5

CCR7+ activated dendritic cells are essential for spontaneous and immunotherapy-driven anti-tumor immunity

4 August 2026

Institute Authors (10)

Erin Richardson, Shih-Chieh Chiang, Massimo Russo, Charles Earnshaw, Anna Pidoux, Poppy Dunn, Sudhakar Sahoo, Antonia Banyard, Natalia Moncaut, Santiago Zelenay

Labs & Facilities

BRU Experimental Team, Computational Biology Support, Genome Editing and Mouse Models, Mass and Flow Cytometry, Transgenic Breeding Team

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Research Group

Cancer Inflammation and Immunity

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https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2

Plasma signals of lung tumor promotion for molecular cancer prevention

25 June 2026

Institute Authors (1)

William Hill

Research Group

Cancer Origins

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https://link.springer.com/article/10.1038/s44319-026-00809-1

PKMYT1 has an important role in the timing and fidelity of chromosome segregation

5 June 2026

Institute Authors (6)

Asma Belbelazi, Charlie Greenaway-Wells, Zoe Edwards, Wendy Trotter, Keren Dawson, Iain Hagan

Research Group

Cell Division

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https://www.nature.com/articles/s42255-026-01514-y

Tissue-specific fibroblast lipid cues impose the rate of epithelial cancer invasion

27 April 2026

Institute Authors (4)

Amaya Virós, Noah Palombo, Charlotte Russell, Claus Jørgensen

Research Group

Skin Cancer & Ageing

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https://www.cell.com/cancer-cell/fulltext/S1535-6108(26)00114-5

Immunometabolic gatekeeping: How tissue metabolism conditions tumor immunity

13 April 2026

Institute Authors (1)

Samra Turajlić

Research Group

Cancer Dynamics

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